Samivio Tablet is a medicine used for the treatment of liver disease associated with reduced bile formation (intrahepatic cholestasis). It protects the liver cells from toxins and helps the liver to perform its normal functions.

Samivio Tablet may be taken with or without food. The dose will depend on the severity of your condition and your body weight. It is best swallowed whole, but you may need to break them to get the correct dose. This medicine needs to be taken regularly to get the most benefit and you may have to take it for several months or longer, so try to get into a routine. Keep using it as prescribed even if your symptoms disappear.

Use of this medicine may cause some common side effects such as headache, dizziness, vomiting, upset stomach, diarrhea, constipation, increased sweating, and insomnia. Not everyone gets side effects. If you are worried about them, or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment. Drink enough water or fluids to stay hydrated in case of severe diarrhea and constipation.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor, all other medicines you are taking. Avoid drinking alcohol as it might increase side effects.

Uses of Samivio Tablet

Treatment of Liver disease

Benefits of Samivio Tablet

In Treatment of Liver disease

Samivio Tablet protects the liver from damage against harmful chemicals, thereby improving overall health of the liver. This helps the liver to perform its normal functions. To make the medicine more effective and for general health benefits, stop smoking, maintain a healthy weight, and do not drink too much alcohol.

Side effects of Samivio Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Samivio

Headache
Dizziness
Vomiting
Upset stomach
Diarrhea
Constipation
Increased sweating
Insomnia (difficulty in sleeping)

How to use Samivio Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Samivio Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Samivio Tablet works

Samivio Tablet contains S-Adenosyl L-Methoinine Disulfate Tosylate, also known as SAMe, a nutritional supplement, that can restore Glutathione concentrations in the liver and also improves liver damage. SAMe is also involved in many biochemical reactions in the human body that regulate the growth, death and differentiation of hepatocytes (liver cells). Because liver function is compromised in people suffering from liver disease, supplementation with Samivio Tablet is beneficial.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Samivio Tablet.

Pregnancy

SAFE IF PRESCRIBED

Samivio Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Samivio Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Samivio Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Samivio Tablet in patients with kidney disease. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Samivio Tablet is safe to use in patients with liver disease. No dose adjustment of Samivio Tablet is recommended.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Samivio Tablet

₹78.0/Tablet

Airrosam 400mg Tablet

Mova Pharmaceutical Pvt Ltd

₹82.5/tablet

6% costlier

Saml 400mg Tablet

Parnasa Mediworld Pvt Ltd

₹88/tablet

13% costlier

Alsame Tablet

Alniche Life Sciences Pvt Ltd

₹75/tablet

4% cheaper

Zemisam 400mg Tablet

Stanley Pharmaceuticals

₹53.9/tablet

31% cheaper

SI Max 400mg Tablet

Trans Life Sciences

₹5.8/tablet

93% cheaper

View all substitutes

Quick tips

Samivio Tablet is prescribed for the treatment of liver disease.
Seek immediate medical attention if you have difficulty breathing after taking the drug.
Samivio Tablet may interfere with surgery. Its use should be discontinued at least two weeks prior to surgery.
Avoid smoking and drinking as it further degrades liver functioning.
You will be regularly monitored for blood creatinine and blood/urine urea levels while on treatment with Samivio Tablet.

Fact Box

Chemical Class

5'-deoxy-5'-thionucleosides

Habit Forming

Patient concerns

Liver disease due to fatty liver

Dr. Deepak Kumar Soni

Ayurveda

Hi kindly share your reports

Fatty liver disease with enlarged liver

Dr. Aanchal Maheshwari

Ayurveda

Take cytozen capsule twice, lavanbhasksr churan half spoon twice

Related lab tests

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Guo T, Chang L, Xiao Y, et al. S-adenosyl-L-methionine for the treatment of chronic liver disease: A systematic review and meta-analysis. PLoS One. 2015;10(3):e0122124. [Accessed 02 Jul. 2021] (online) Available from:
Noureddin M, Sander-Struckmeier S, Mato JM. Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: A systematic review. World J Hepatol. 2020;12(2):46-63. [Accessed 02 Jul. 2021] (online) Available from:

Marketer details

Name: Wellvio Healthcare Pvt Ltd

Address: 730 JMD Megapolis Sohna Road Gurugram 122018

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.