Amab Injection is a medicine used to treat a variety of conditions such as ankylosing spondylitis, rheumatoid arthritis, psoriasis, ulcerative colitis, and Crohn’s disease. It provides relief from swelling, pain, and redness associated with various disorders and improves physical function.

Amab Injection is used to treat joint diseases leading to severe painful swelling and redness of the joints that can lead to difficulty in movement.

Uses of Amab Injection

Benefits of Amab Injection

In Ankylosing spondylitis

Ankylosing spondylitis is a rare type of arthritis that affects the spine or larger joints. It usually starts in your lower back and can spread up to your neck or damage joints in other parts of your body. Amab Injection helps reduce pain, stiffness and swelling in your spine and joints. It helps improve flexibility and prevents disease progression. This will help you lead a better and active life.

In Rheumatoid arthritis

Amab Injection reduces pain, stiffness, and swelling in your joints and slows down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. The medicine is given as an injection is given by a doctor or nurse and should not be self-administered.

In Psoriasis

Psoriasis is a condition where the skin cells in the body grow too quickly and form scales and dry patches. They can grow anywhere, but most appear on the scalp, elbows, knees, and lower back. Amab Injection reduces the scaly, itchy patches which may develop on the different parts of the body. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Ulcerative colitis

Ulcerative colitis is a disease of the large intestine (colon) and rectum in which the lining of the bowel becomes red and swollen. This can lead to bleeding, frequent diarrhea and abdominal pain. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You should drink plenty of fluids while taking on treatment with this medicine to make sure you stay hydrated.

In Crohn’s disease

Crohn’s disease is a chronic (long-term) inflammatory disease of the intestines. The most common symptoms are diarrhea and pain in your abdomen. Amab Injection helps reduce the inflammation, relieve the symptoms, and prevent them from coming back.

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Side effects of Amab Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amab

Headache
Sinus inflammation
Rash
Upper respiratory tract infection
Injection site reaction

How to use Amab Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol

SAFE

Consuming alcohol with Amab Injection does not cause any harmful side effects.

Pregnancy

SAFE IF PRESCRIBED

Amab Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Amab Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Amab Injection may cause side effects which could affect your ability to drive.
Amab Injection may cause room spinning sensation and vision disturbances. This may affect your driving ability.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Amab Injection in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Amab Injection in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Amab Injection

₹12.0/Injection

Adalirel 40mg Injection

Reliance Life Sciences

₹22000/injection

183233% costlier

Envira 40mg Injection

Emcure Pharmaceuticals Ltd

₹23437.5/injection

195212% costlier

Mabura 40mg Injection

Hetero Drugs Ltd

₹25000/injection

208233% costlier

Plamumab 40mg Injection

Cipla Ltd

₹19800/injection

164900% costlier

Adaly Injection

Glenmark Pharmaceuticals Ltd

₹24900/injection

207400% costlier

Quick tips

It is given by injection under the skin (via subcutaneous).
Take it as per the dose and duration suggested by the doctor.
Inform your doctor immediately if you notice severe rash, hives, swelling of hands or face and shortness of breath.
Store the pen in the refrigerator. When refrigeration is not possible, you can also keep your pen at room temperature (less than 30°C) for up to 2 weeks. Do not freeze it.
Do not stop taking the medication suddenly without talking to your doctor first.

Fact Box

Chemical Class

Monoclonal antibody (mAb)

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Biologics

Patient concerns

Suffering from ultratics colitis i have done colonoscopy test 04 months back From 05 months how many months I have to take medicines is it cure completely

Dr. Kunal Parasar

Surgical Gastroenterology

Ulcerative colitis is a lifelong disease with remission and exacerbations. Durations of remission cant b predicted all d time

Hi, I was diagnosed for Ulcerative Colitis in 2009. I was administered with Mesacol , I was back to normal. In past 1 month , after having food lunch or dinner I feel uneasy such as indigestion, having to force for motions next day. Sometimes Iam unable to pass motions. I feel tired also. Pls suggest.

Dr. Kunal Parasar

Surgical Gastroenterology

Ulcerative colitis is a lifong disease q with remission and exacerbation . U should b under constant follow up of ur gastroenterologist

Suffering from severe lower back pain since 6 years. As per MRI it is lumbar spondylosis,but Doctor told that it is one of the types of arthritis in which bridge is getting formed on spine Is there any permanent solution .at present taking Sazo 500 twice a day

Dr. Akshat Goel

Orthopaedics

It's called Ankylosing spondylitis". no permanent cure for this All you need to do is to exercise each and every joint of your body regularly "Along with the medication

FAQs

What type of drug is Amab Injection?

Amab Injection belongs to a class of drugs name TNF blockers. It reduces joint damage by reducing swelling and improves joint function.

What benefit can you expect from your treatment with Amab Injection?

You may notice a lessening of joint swelling, pain, and stiffness, often within the first 8 weeks of starting the treatment.

Can Amab Injection weaken your immune system?

Amab Injection is a TNF blocker medicine that can lower the ability of your immune system to fight infections. Inform your doctor if you have been suffering from any infections before taking this medicine.

Can Amab Injection be used with other arthritis medicines?

Amab Injection is a biological disease-modifying antirheumatic drug (bDMARD) and may be used with other medicines like methotrexate (DMARDs); prednisolone (steroid); naproxen or ibuprofen (anti-inflammatory medicines) and paracetamol (pain killers). However, it cannot be used with other bDMARDs. Your doctor will be able to give you more information on this.

Should Amab Injection be stopped before any surgery?

Yes, treatment with this medicine should be stopped before surgery. It can start again after the operation at a time decided by your surgeon and rheumatologist (often once the wound has healed and there is no infection).

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 633.
Wallace JL, Sharkey KA. Pharmacotherapy of Inflammatory Bowel Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1359.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 22-24.
Adalimumab. North Chicago, Illinois: Abbott Laboratories; 2002 [revised Jan. 2008]. [Accessed 25 Jan. 2019] (online) Available from:
Adalimumab. North Chicago, Illinois: AbbVie Inc.; 2002 [revised May 2014]. [Accessed 02 Apr. 2019] (online) Available from:

Marketer details

Name: Dr Reddy's Laboratories Ltd

Address: Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA

Country of origin: India

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