Glyroz

Take Gliclazide before meals or exactly as instructed by your doctor. There is evidence stating that Gliclazide works best at controlling post meal high blood sugar levels when taken 30 minutes before breakfast. So, if you are supposed to take it once daily, take it in the morning before breakfast with a glass of water.

No, Gliclazide is not the same as metformin. Although both these oral medicines are used in the treatment of type 2 diabetes, the way they work to reduce the sugar levels are different. While Gliclazide acts by increasing the secretion of insulin by the pancreas, metformin acts by improving the functioning and effectiveness of the insulin already available in the body.

Yes, Gliclazide and metformin can be taken at the same time but only if prescribed by the doctor. Your doctor may have prescribed taking the two together to control your uncontrolled sugar levels. However, taking the two together may cause low blood sugar which may also occur if you delay or miss a meal, exercise more than usual or take it with insulin. Follow the instructions given by your doctor strictly to avoid such complications.

No, Gliclazide is not harmful if your kidney function is normal. Any previous case of kidney problem should be informed to the doctor, so that the use of Gliclazide can be assessed. This is done in order to analyze whether Gliclazide can be given or not because it is principally excreted by the kidney. If you have kidney problems you will be started at a lower dose.

Rosiglitazone when added to Glimepiride in patients with diabetes mellitus, has been found to significantly reduce plasma lipid levels and significant improvement in blood glucose control related to a reduction in the insulin resistance.

Rosiglitazone is an anti-diabetes drug used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. Pioglitazone acts as an insulin sensitizer and decreases the extent of insulin resistance in the body too.

Rosiglitazone increases the permeability of fluid in tiny blood vessels called capillaries. This results in easier movement of fluids across the membrane and their consequent accumulation, resulting in oedema (puffiness). Also, Pioglitazone causes increased sodium and water reabsorption from the kidney that contributes to the oedema.

Rosiglitazone can cause fluid retention and edema. Consequently, there is a lot of fluid in the body (fluid overload). As a result, it may precipitate heart failure (which worsens with fluid overload in those at risk).

Rosiglitazone, either alone or as add-on therapy to conventional treatments, could clinically benefit patients of major depression according to a study