Tissue Transglutaminase Antibody - IgA near me in Ahmedabad

(tTG IgA)

This test is for

Male, Female

Test Preparation

No special preparation required

Understanding Tissue Transglutaminase Antibody - IgA in Ahmedabad

What is Tissue Transglutaminase Antibody - IgA in Ahmedabad?

The tissue transglutaminase IgA (tTG-IgA) test is a blood test used to diagnose celiac disease. Celiac disease results from an immune-mediated inflammatory process that damages the small intestine. This disease is triggered by eating gluten in diet.
The tTG-IgA test is advised if you have symptoms suggestive of celiac disease such as pain in the abdomen, diarrhea, and weight loss, or if you have a family history of celiac disease. It is also done to check for treatment efficacy for celiac disease in some cases.
This test is the most sensitive test for celiac disease for both kids older than 3 years as well as adults.

What does Tissue Transglutaminase Antibody - IgA measure?

The tissue transglutaminase antibody - IgA test measures self-generated antibodies present in the blood which are produced by the body in response to autoimmune disorders such as celiac disease and other gluten-sensitive conditions. In celiac disease, an inappropriate immune response is generated to counter the presence of gluten. Gluten is a protein which is found in wheat, rye, and barley.

Due to the immune response produced by the body, there is inflammation of the small intestine which leads to damage and destruction of the villi that lines the walls of the intestine. Villi are finger-like structures present in the small intestine. These are responsible for increasing the surface area of the intestine and help in digestion of food. They allow various nutrients, vitamins, minerals, electrolytes, and fluids to be absorbed into the body.

If a person suffering from celiac disease get exposed to gluten content, the body in response starts producing antibodies. These antibodies cause inflammation which damages the villi. This damage will further impact the body’s ability to absorb food. In such conditions, the body begins to develop signs and symptoms which are associated with malnutrition and malabsorption.