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Content created by
Written by
Dr. Betina Chandolia
BDS, MDS - Oral Pathology and Microbiology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Estriol Unconjugated

(E3)
This test is for
Male, Female
Test Preparation
  1. No special preparation required

Understanding Estriol Unconjugated


What is Estriol Unconjugated?

Unconjugated estriol (uE3) is a form of oestrogen (hormone) produced by the fetus (unborn baby) through metabolism. Estriol levels are used to determine birth defects and chromosomal variations in babies. Estriol is ejected from the placenta (an organ acting as the protective covering for the fetus) into the mother’s blood, and measured as unconjugated uE3. This test is mainly used for diagnosing Down syndrome.

A blood sample is shared with the lab for analysis. There are no specific risks involved in taking this test, and it is considered one of the best ways to analyse an unborn baby’s health.

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Estriol Unconjugated


Frequently Asked Questions about Estriol Unconjugated

Q. Is there any risk associated with this test?

There is no risk associated with the test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.

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