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NT-Pro BNP

NT-Pro BNP

For men & women
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NT-Pro BNP test is used to measure the amount of BNP (B-Type Natriuretic peptide) and NT-Pro BNP (N-Terminal-Pro) in the blood. These molecules are released into the blood stream in response to any stress encountered by the heart. Elevated level of these molecules is an indicator of excessive pressure on heart, heart faliure, or other acute heart conditions.

This test is recommended generally after a heart attack or to those undergoing any heart disease treatment.

A normal value of NT-Pro-BNP should be under 100pg/mL. Any value higher than this is considered fatal and an immediate medical intervention is mandatory.

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What does NT-Pro BNP measure?

The NT-Pro BNP Test measures the levels of the protein BNP in blood. The NT-Pro BNP (N-terminal pro b-type natriuretic peptide) is a substance secreted by the left ventricle of the heart due to the stretching of the heart chamber while pumping blood. It helps in the relaxation of blood vessels for smooth blood flow. The heart continuously secretes a precursor substance called pro-BNP which is converted to BNP to maintain a low constant level in blood. In case of congestive heart failure, the heart works harder to pump blood causing extra pressure in the heart muscles. This leads to an increase in the production of BNP to help stimulate the blood vessels to relax and reduce the pressure on the heart. This increased production of BNP could be due to other conditions which affect the circulatory system like blockages in blood vessels.

The B-Type Natriuretic Peptide was initially named the Brain Type Natriuretic Peptide since it was first detected in the brain tissues. Later, it was renamed to B-Type to distinguish it from Atrial or A-Type Natriuretic Peptide (ANP), which is another substance with similar function also produced in the heart.


FAQs related to NT-Pro BNP

Heart failure can be indicated by symptoms such as difficulty in breathing, shortness of breath, feeling tired, and swelling (edema) in the feet, ankles, legs, and abdomen.
Congestive heart failure is a progressive condition (increase in intensity with time). In this, the heart muscles are unable to efficiently pump blood in sufficient quantities required for the rest of the body. Congestive heart failure can be caused by a number of factors such as high blood pressure (hypertension) and coronary artery diseases, where cholesterol deposition occurs on the inner wall of the blood vessels, causing a blockage in blood supply. It is observed that there are certain conditions which affect the heart valves and make them ineffective, which as a result lead to congestive heart failure. It should be noted that congestive heart failure can also be seen in conditions which are not directly related to the heart such as diabetes, obesity, severe infections, etc.
The doctor may suggest other tests if the result of Nt-pro BNP Test comes above or below the normal range. These tests include ANP test, lipid profile test, chest X-ray, electrocardiogram, and echocardiogram.
The levels of NT-pro BNP can increase in conditions such as heart failure, asymptomatic left ventricular dysfunction, arterial and pulmonary hypertension, cardiac hypertrophy, valvular heart disease, arrhythmia, and acute coronary syndrome. Along with that, conditions like acute and chronic renal failure, liver cirrhosis, hyperaldosteronism, and Cushing’s syndrome can show increased levels of NT-pro BNP.
The healthcare provider takes a blood sample from the arm. The site from where the blood is to be withdrawn is cleaned with a swab of rubbing alcohol. This is then followed by inserting a small needle which has a tube attached to it for collecting blood. Once the sufficient blood for analysis is withdrawn, the needle is removed. The site is then covered with a gauze pad.
As such there is no risk but in few cases, bruising, bleeding, and infection at the puncture site can be seen. In very few cases, there can be swelling of the vein after the blood is withdrawn.
Content created by
Written by:
Dr. Lipika Khurana
BDS, PGDHHM
Reviewed by:
Dr. Swati Gupta (Anand)
MBBS, MD Lab Medicine
Want to know moreRead our editorial policy
Last Updated9th Feb 2026

NT-Pro BNP test price for other cities

Price inAhmedabadRs. 2750
Price inAllahabadRs. 2750
Price inBangaloreRs. 2750
Price inBhopalRs. 2750
Price inChandigarhRs. 2750

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Contains 1 test
NT-Pro BNP