In case of HIV-1 infection, Tenofovir disoproxil fumarate may reduce the risk of passing the virus to others, but the chances of infecting others still persist. However, in case of HBV infection, Tenofovir disoproxil fumarate has not proven to reduce risk of transferring the virus to others. Therefore, the patients of both HIV-1 infection and HBV infection should practice safe sex and should not share dirty needles.