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Zavicefta Injection
Ceftazidime (2gm)+ Avibactam (0.5mg)
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Zavicefta Injection is an antibiotic medicine used in the treatment of severe bacterial infections of the lungs, stomach, and urinary tract. It may be used alone or in combination with other antibiotics, like metronidazole, to treat various bacterial infections in both children and adults.
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 12 Nov 2024 | 01:02 AM (IST)
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 12 Nov 2024 | 01:02 AM (IST)
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General Information
The content is shown in English



Product introduction
Zavicefta Injection is given as an injection into a vein by a trained healthcare professional. It should be used regularly as prescribed by your doctor. Do not skip any doses and finish the full course of the treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.
The most common side effects of Zavicefta Injection include diarrhea, nausea, vomiting, rash, and infusion site phlebitis. These are usually mild but let your doctor know if they bother you or last more than a few days. This medicine may also cause diarrhea as a side effect. Taking probiotics along with this medicine may provide help.
Before using it, tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your doctor know about all the other medicines you are taking, as they may affect or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it.
The most common side effects of Zavicefta Injection include diarrhea, nausea, vomiting, rash, and infusion site phlebitis. These are usually mild but let your doctor know if they bother you or last more than a few days. This medicine may also cause diarrhea as a side effect. Taking probiotics along with this medicine may provide help.
Before using it, tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your doctor know about all the other medicines you are taking, as they may affect or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it.
Uses of Zavicefta Injection
Benefits of Zavicefta Injection
Treatment of Bacterial infections
Zavicefta Injection works by killing bacteria that can cause serious infections. It is used to treat many different types of bacterial infections, such as infections of the lung (pneumonia), stomach, and urinary tract. It is given by a doctor or nurse into a vein and should not be self-administered. Zavicefta Injection usually makes you feel better very quickly, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.
Zavicefta Injection works by killing bacteria that can cause serious infections. It is used to treat many different types of bacterial infections, such as infections of the lung (pneumonia), stomach, and urinary tract. It is given by a doctor or nurse into a vein and should not be self-administered. Zavicefta Injection usually makes you feel better very quickly, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.
Side effects of Zavicefta Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zavicefta
- Diarrhea
- Nausea
- Vomiting
- Rash
- Infusion site vesicles
How to use Zavicefta Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Zavicefta Injection works
Zavicefta Injection is a combination of ceftazidime and avibactam. Ceftazidime is a bactericidal agent that acts by inhibiting bacterial cell wall synthesis. Avibactam works by preventing bacteria from breaking down ceftazidime.
Quick tips
- Diarrhea may occur as a side effect of Zavicefta Injection but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Stick to simple meals, avoid rich or spicy food, and drink plenty of water while taking Zavicefta Injection.
- Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat, or tongue, or breathing difficulties while taking Zavicefta Injection.
- Zavicefta Injection can cause confusion, hallucinations, seizures, and coma. Seek immediate medical attention for treatment, dosage adjustment, or discontinuation of the treatment.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Zavicefta Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Zavicefta Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CAUTION
Zavicefta Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving
CONSULT YOUR DOCTOR
It is not known whether Zavicefta Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney
CAUTION
Zavicefta Injection should be used with caution in patients with kidney disease. Dose adjustment of Zavicefta Injection may be needed. Please consult your doctor.

Liver
SAFE IF PRESCRIBED
Zavicefta Injection is safe to use in patients with liver disease. No dose adjustment of Zavicefta Injection is recommended.
Frequently asked questions
Zavicefta Injection is given as an injection through the veins (IV) to patients in a hospital. The total infusion time is typically 2 hours.
The typical dose for adults is 2.5 grams injected through the veins (IV) every 8 hours. The dose for children is based on age and is also given every 8 hours. Your dose might be lower or less frequent if you have kidney problems.
Zavicefta Injection should not be used in pediatric patients aged under 3 months.
Before the administration of Zavicefta Injection let your doctor know if:<br>a. you are allergic to any medicines, especially antibiotics.<br>b. you have any kidney problems.
Yes, diarrhea is a common problem caused by antibacterial drugs, including Zavicefta Injection. If severe watery or bloody diarrhea develops, contact your doctor immediately since it might be a sign of a serious intestinal infection.
It is important to seek treatment because an untreated bacterial infection can lead to serious problems.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Related lab tests
References
- Ceftazidime and avibactam [Prescribing Information]. Verona, Italy: GlaxoSmithKline Manufacturing S.p.A.; 2019. [Accessed 19th Nov. 2022] (online) Available from:
- Ceftazidime and avibactam [Summary of Product Characteristics]. Verona, Italy: ACS Dobfar S.p.A.; 2016. [Accessed 19th Nov. 2022] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Zavicefta Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Zavicefta Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- Complete Blood Count
- Glucose - Fasting
- Thyroid profile Total
- Glycosylated Hemoglobin
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-OH)
- Urine Routine & Microscopy
- Coronavirus Covid-19 Test (RT-PCR technique)
- Liver Function Test
- Kidney Function Test
- Thyroid Stimulating Hormone, Ultrasensitive
- Erythrocyte Sedimentation Rate
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Calcium
- Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- Kidney Function Test with Electrolytes
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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