Pexep 40 Tablet

Paroxetine (40mg)

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Pexep 40 Tablet is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is widely prescribed to treat depression and anxiety-related conditions like obsessive-compulsive disorder, and panic disorder.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS,
Last updated on 12 Nov 2024 | 01:04 AM (IST)

Gurgaon

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Pexep 40 Tablet

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Parotin 40mg Tablet

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Paroxetine (40mg)

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General Information

Contains

Paroxetine (40mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Pexep 40 Tablet helps many people to recover from depression by improving their mood and relieving anxiety and tension. It can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms.

Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse or you may suffer from unpleasant withdrawal symptoms (anxiety, restlessness, palpitations, dizziness, sleep disturbances, etc).

To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.

Some common side effects of Pexep 40 Tablet include nausea, fatigue, dry mouth, loss of appetite, increased sweating, dizziness, nervousness, tremors, insomnia (difficulty in sleeping), and constipation. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.

Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Please tell your doctor about all the medicines you are taking to make sure you are safe.

Uses of Pexep Tablet

Benefits of Pexep Tablet

Treatment of Depression
Pexep 40 Tablet works by increasing the level of a chemical called serotonin in the brain. This improves your mood, relieves anxiety, tension, and helps you sleep better. It has fewer side effects than older antidepressants. It usually takes 4-6 weeks for this medicine to work so you need to keep taking it even if you feel it is not working. Do not stop taking it, even if you feel better unless your doctor advises you to.

Treatment of Panic disorder
Pexep 40 Tablet can help relieve symptoms of many panic disorders including panic attacks. It can help you feel calmer and improve your ability to deal with problems. Do not stop taking it, even when you feel better, unless your doctor advises you to.

Treatment of Anxiety disorder
Pexep 40 Tablet helps relieve symptoms of many anxiety disorders including obsessive-compulsive disorder and generalized anxiety disorder by increasing the level of a chemical called serotonin in your brain. It has fewer side effects than older antidepressants and is normally taken once a day. It helps you feel calm with a better ability to deal with problems. Exercise and a healthy diet can also improve your mood. Keep taking the medicine until your doctor advises you to stop.

Side effects of Pexep Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pexep

Nausea
Fatigue
Dryness in mouth
Loss of appetite
Increased sweating
Dizziness
Nervousness
Tremors
Low sexual desire
Insomnia (difficulty in sleeping)
Confusion
Constipation
Erectile dysfunction
Delayed ejaculation
Decreased libido

How to use Pexep Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pexep 40 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Pexep Tablet works

Pexep 40 Tablet is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of panic disorder, anxiety, and obsessive-compulsive disorder.

All substitutes for Pexep 40 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

It can take 2-3 weeks for Pexep 40 Tablet to start working.
Do not stop treatment suddenly as this may cause upset stomach, flu-like withdrawal symptoms and sleep disturbance.
If your doctor asks you to stop Pexep 40 Tablet, you should reduce the dose slowly over 4 weeks.
Avoid consuming alcohol when taking Pexep 40 Tablet, as it may cause excessive drowsiness and calmness.
The addiction/dependence potential of Pexep 40 Tablet is very less.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Pexep 40 Tablet.

Pregnancy

UNSAFE

Pexep 40 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Pexep 40 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Pexep 40 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Pexep 40 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pexep 40 Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Pexep 40 Tablet should be used with caution in patients with liver disease. Dose adjustment of Pexep 40 Tablet may be needed. Please consult your doctor.

Interaction with drugs

Taking Pexep with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Cyproheptadine (Oral Route)

Library explanation 106

Frequently asked questions

After how many days of taking Pexep 40 Tablet will I start feeling better?

You may start to see an improvement in your symptoms after 1-2 weeks of starting the treatment. In case you do not see any improvement, do not stop the medicine and consult your doctor. It may take around 4-6 weeks to see the full benefits of the medicine.

I feel that my symptoms have worsened after having started taking Pexep 40 Tablet. Can I stop it on my own or do I need to consult the doctor?

No, do not stop taking Pexep 40 Tablet abruptly, without consulting your doctor. This is a common problem with Pexep 40 Tablet that initially you may feel that your symptoms have worsened but the benefits start appearing after 1-2 weeks. If the worsening does not improve even after 1-2 weeks, you must consult your doctor.

Can Pexep 40 Tablet affect my sex life?

Yes, Pexep 40 Tablet use may affect your sex life. It can cause decreased sexual desire and inability to reach orgasm in both men and women. Additionally, men may even experience abnormal erection and ejaculation.

What is the effect of Pexep 40 Tablet on children?

Pexep 40 Tablet should not be used in children under 18 years of age. The reason being, patients under 18 have an increased risk of experiencing side effects such as suicidal thoughts, aggression, oppositional behavior and anger when they take Pexep 40 Tablet. If your doctor has prescribed Pexep 40 Tablet for your child and you are worried about these side effects, discuss it with your doctor.

I have been taking tamoxifen for breast cancer. Can I take Pexep 40 Tablet with it?

No, you should not take Pexep 40 Tablet if you are receiving tamoxifen. Tamoxifen often causes hot flashes (episodes of feeling extremely hot), which can be treated with Pexep 40 Tablet. But Pexep 40 Tablet may reduce the effectiveness of tamoxifen and can lead to recurrence of breast cancer.

Do I need to be careful while taking Pexep 40 Tablet if I am a diabetic?

Yes, you need to be careful while taking this medicine if you are a diabetic. Pexep 40 Tablet may alter your blood sugar levels and your dose of insulin or antidiabetic medicines may need adjustment. Talk to your doctor regarding this and keep a regular check on your blood sugar levels.

Fact Box

Chemical Class

Phenylpiperidine Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Selective Seretonin Reuptake inhibitors (SSRIs)

References

Stahl SM, editor. Paroxetine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 513-19.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1060-69.
Paroxetine.Miami, Florida:Noven Therapeutics; 2003 [revised 06-2013]. [Accessed 25 Mar 2019] (online) Available from:
Chaves RG, Lamounier GA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 25 Mar. 2019] (online) Available from:
Paroxetine. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2008 [revised 25 Nov. 2018]. [Accessed 25 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Paroxetine. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
Paroxetine [Product Monograph]. Mississauga, Ontario: GlaxoSmithKline Inc.; 2022. [Accessed 03 Aug. 2023] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India

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Why we need a prescription?

Pexep 40 Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Pexep Tablet

Benefits of Pexep Tablet

Side effects of Pexep Tablet

How to use Pexep Tablet

How Pexep Tablet works

All substitutes for Pexep 40 Tablet

Parytine 40mg Tablet

Parot 40mg Tablet

Parotin 40mg Tablet

Pari 40mg Tablet

Xepar 40mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cyproheptadine (Oral Route)

Frequently asked questions

After how many days of taking Pexep 40 Tablet will I start feeling better?

I feel that my symptoms have worsened after having started taking Pexep 40 Tablet. Can I stop it on my own or do I need to consult the doctor?

Can Pexep 40 Tablet affect my sex life?

What is the effect of Pexep 40 Tablet on children?

I have been taking tamoxifen for breast cancer. Can I take Pexep 40 Tablet with it?

Do I need to be careful while taking Pexep 40 Tablet if I am a diabetic?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

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