

Perilife 12.5mg Tablet
Paroxetine (12.5mg)
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Perilife 12.5mg Tablet is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is widely prescribed to treat depression and anxiety-related conditions like obsessive-compulsive disorder, and panic disorder.
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS,
Last updated on 12 Nov 2024 | 01:06 AM (IST)
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS,
Last updated on 12 Nov 2024 | 01:06 AM (IST)
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General Information
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Product introduction
Perilife 12.5mg Tablet helps many people to recover from depression by improving their mood and relieving anxiety and tension. It can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms.
Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse or you may suffer from unpleasant withdrawal symptoms (anxiety, restlessness, palpitations, dizziness, sleep disturbances, etc).
To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.
Some common side effects of Perilife 12.5mg Tablet include nausea, fatigue, dry mouth, loss of appetite, increased sweating, dizziness, nervousness, tremors, insomnia (difficulty in sleeping), and constipation. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.
Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Please tell your doctor about all the medicines you are taking to make sure you are safe.
Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse or you may suffer from unpleasant withdrawal symptoms (anxiety, restlessness, palpitations, dizziness, sleep disturbances, etc).
To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.
Some common side effects of Perilife 12.5mg Tablet include nausea, fatigue, dry mouth, loss of appetite, increased sweating, dizziness, nervousness, tremors, insomnia (difficulty in sleeping), and constipation. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.
Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Please tell your doctor about all the medicines you are taking to make sure you are safe.
Uses of Perilife Tablet
- Treatment of Depression
- Treatment of Panic disorder
- Treatment of Anxiety disorder
Benefits of Perilife Tablet
Treatment of Depression
Perilife 12.5mg Tablet works by increasing the level of a chemical called serotonin in the brain. This improves your mood, relieves anxiety, tension, and helps you sleep better. It has fewer side effects than older antidepressants. It usually takes 4-6 weeks for this medicine to work so you need to keep taking it even if you feel it is not working. Do not stop taking it, even if you feel better unless your doctor advises you to.
Perilife 12.5mg Tablet works by increasing the level of a chemical called serotonin in the brain. This improves your mood, relieves anxiety, tension, and helps you sleep better. It has fewer side effects than older antidepressants. It usually takes 4-6 weeks for this medicine to work so you need to keep taking it even if you feel it is not working. Do not stop taking it, even if you feel better unless your doctor advises you to.
Treatment of Panic disorder
Perilife 12.5mg Tablet can help relieve symptoms of many panic disorders including panic attacks. It can help you feel calmer and improve your ability to deal with problems. Do not stop taking it, even when you feel better, unless your doctor advises you to.
Perilife 12.5mg Tablet can help relieve symptoms of many panic disorders including panic attacks. It can help you feel calmer and improve your ability to deal with problems. Do not stop taking it, even when you feel better, unless your doctor advises you to.
Treatment of Anxiety disorder
Perilife 12.5mg Tablet helps relieve symptoms of many anxiety disorders including obsessive-compulsive disorder and generalized anxiety disorder by increasing the level of a chemical called serotonin in your brain. It has fewer side effects than older antidepressants and is normally taken once a day. It helps you feel calm with a better ability to deal with problems. Exercise and a healthy diet can also improve your mood. Keep taking the medicine until your doctor advises you to stop.
Perilife 12.5mg Tablet helps relieve symptoms of many anxiety disorders including obsessive-compulsive disorder and generalized anxiety disorder by increasing the level of a chemical called serotonin in your brain. It has fewer side effects than older antidepressants and is normally taken once a day. It helps you feel calm with a better ability to deal with problems. Exercise and a healthy diet can also improve your mood. Keep taking the medicine until your doctor advises you to stop.
Side effects of Perilife Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Perilife
- Nausea
- Fatigue
- Dryness in mouth
- Loss of appetite
- Increased sweating
- Dizziness
- Nervousness
- Tremors
- Low sexual desire
- Insomnia (difficulty in sleeping)
- Confusion
- Constipation
- Erectile dysfunction
- Delayed ejaculation
- Decreased libido
How to use Perilife Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Perilife 12.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Perilife Tablet works
Perilife 12.5mg Tablet is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of panic disorder, anxiety, and obsessive-compulsive disorder.
All substitutes for Perilife 12.5mg Tablet
For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- It can take 2-3 weeks for Perilife 12.5mg Tablet to start working.
- Do not stop treatment suddenly as this may cause upset stomach, flu-like withdrawal symptoms and sleep disturbance.
- If your doctor asks you to stop Perilife 12.5mg Tablet, you should reduce the dose slowly over 4 weeks.
- Avoid consuming alcohol when taking Perilife 12.5mg Tablet, as it may cause excessive drowsiness and calmness.
- The addiction/dependence potential of Perilife 12.5mg Tablet is very less.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Perilife 12.5mg Tablet.

Pregnancy
UNSAFE
Perilife 12.5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding
CONSULT YOUR DOCTOR
Perilife 12.5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving
UNSAFE
Perilife 12.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
CAUTION
Perilife 12.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Perilife 12.5mg Tablet may be needed. Please consult your doctor.

Liver
CAUTION
Perilife 12.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Perilife 12.5mg Tablet may be needed. Please consult your doctor.
Interaction with drugs
Taking Perilife with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Frequently asked questions
You may start to see an improvement in your symptoms after 1-2 weeks of starting the treatment. In case you do not see any improvement, do not stop the medicine and consult your doctor. It may take around 4-6 weeks to see the full benefits of the medicine.
No, do not stop taking Perilife 12.5mg Tablet abruptly, without consulting your doctor. This is a common problem with Perilife 12.5mg Tablet that initially you may feel that your symptoms have worsened but the benefits start appearing after 1-2 weeks. If the worsening does not improve even after 1-2 weeks, you must consult your doctor.
Yes, Perilife 12.5mg Tablet use may affect your sex life. It can cause decreased sexual desire and inability to reach orgasm in both men and women. Additionally, men may even experience abnormal erection and ejaculation.
Perilife 12.5mg Tablet should not be used in children under 18 years of age. The reason being, patients under 18 have an increased risk of experiencing side effects such as suicidal thoughts, aggression, oppositional behavior and anger when they take Perilife 12.5mg Tablet. If your doctor has prescribed Perilife 12.5mg Tablet for your child and you are worried about these side effects, discuss it with your doctor.
No, you should not take Perilife 12.5mg Tablet if you are receiving tamoxifen. Tamoxifen often causes hot flashes (episodes of feeling extremely hot), which can be treated with Perilife 12.5mg Tablet. But Perilife 12.5mg Tablet may reduce the effectiveness of tamoxifen and can lead to recurrence of breast cancer.
Yes, you need to be careful while taking this medicine if you are a diabetic. Perilife 12.5mg Tablet may alter your blood sugar levels and your dose of insulin or antidiabetic medicines may need adjustment. Talk to your doctor regarding this and keep a regular check on your blood sugar levels.
Fact Box
Chemical Class
Phenylpiperidine Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Selective Seretonin Reuptake inhibitors (SSRIs)
References
- Stahl SM, editor. Paroxetine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 513-19.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1060-69.
- Paroxetine.Miami, Florida:Noven Therapeutics; 2003 [revised 06-2013]. [Accessed 25 Mar 2019] (online) Available from:
- Chaves RG, Lamounier GA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 25 Mar. 2019] (online) Available from:
- Paroxetine. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2008 [revised 25 Nov. 2018]. [Accessed 25 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Paroxetine. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
- Paroxetine [Product Monograph]. Mississauga, Ontario: GlaxoSmithKline Inc.; 2022. [Accessed 03 Aug. 2023] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Verbiance Lifesciences Private Limited
Address: C/O MR. VIKAS RASTOGI, H. NO. 8,SECTOR 6 GREEN PARK, BISALPUR ROAD BAREILLY Bareilly UP 243006 IN
Address: C/O MR. VIKAS RASTOGI, H. NO. 8,SECTOR 6 GREEN PARK, BISALPUR ROAD BAREILLY Bareilly UP 243006 IN
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Perilife 12.5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Perilife 12.5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- Complete Blood Count
- Glucose - Fasting
- Thyroid profile Total
- Glycosylated Hemoglobin
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-OH)
- Urine Routine & Microscopy
- Coronavirus Covid-19 Test (RT-PCR technique)
- Liver Function Test
- Kidney Function Test
- Thyroid Stimulating Hormone, Ultrasensitive
- Erythrocyte Sedimentation Rate
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Calcium
- Creatinine
- Diabetes Screening
- Kidney Function Test with Electrolytes
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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