Naprosafe D 250 Tablet is a combination of two medicines used in the prevention of migraines. It blocks the release of certain chemical messengers that cause pain, inflammation, and fever. It also blocks the signals in the brain that cause nausea and vomiting associated with migraines.

Naprosafe D 250 Tablet is a combination of two medicines: Naprosafe D 250 Tablet1 and Naprosafe D 250 Tablet2.

Uses of Naprosafe D Tablet

Prevention of Migraine

Benefits of Naprosafe D Tablet

In Prevention of Migraine

Naprosafe D 250 Tablet blocks chemicals responsible for pain sensation and also blocks signals that cause nausea/vomiting associated with migraines. By preventing and reducing the frequency of migraine headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Naprosafe D Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Naprosafe D

Flu-like symptoms
Indigestion
Dryness in mouth

How to use Naprosafe D Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Naprosafe D 250 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Naprosafe D 250 Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Naprosafe D 250 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Naprosafe D 250 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

UNSAFE

Naprosafe D 250 Tablet may cause side effects which could affect your ability to drive.
Naprosafe D 250 Tablet may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.

Kidney

CAUTION

Naprosafe D 250 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Naprosafe D 250 Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Naprosafe D 250 Tablet should be used with caution in patients with liver disease. Dose adjustment of Naprosafe D 250 Tablet may be needed. Please consult your doctor.
Use of Naprosafe D 250 Tablet is not recommended in patients with moderate and severe liver disease.

What if you forget to take Naprosafe D Tablet?

If you miss a dose of Naprosafe D 250 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Naprosafe D 250 Tablet

₹6.1/Tablet

Napra D 250 Tablet

Intas Pharmaceuticals Ltd

₹6.5/tablet

7% costlier

Macprox DP 250 Tablet

Macleods Pharmaceuticals Pvt Ltd

₹6.21/tablet

2% costlier

Xenadom 250 Tablet

Icon Life Sciences

₹7.6/tablet

25% costlier

Naprodom 250mg Tablet

Crescent Therapeutics Ltd

₹4.94/tablet

19% cheaper

Minado Tablet

Tas Med India Pvt Ltd

₹4.57/tablet

25% cheaper

View all substitutes

Quick tips

Naprosafe D Tablet

You have been prescribed Naprosafe D 250 Tablet for prevention of migraine headaches.
Do not take it to treat an acute attack of migraine.
Some tips that may help avoid a migraine attack:
- Have your meals at the same time everyday
- Avoid bright lights and extreme temperatures
- Avoid loud music and noisy places
- Avoid chocolates, cheese, processed food, alcohol and smoking
- Get enough sleep and avoid stress
It may cause sleepiness. Do not drive or do anything that requires mental focus until you know how Naprosafe D 250 Tablet affects you.
Avoid consuming alcohol as it may cause new and worse headaches.
Keep taking it every day, as prescribed by your doctor, even if you do not have any symptoms.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

I am facing issue of headache from last 3-4 years.i have consulted allopathy and they have given me sibelum 10 for migrane and asked to take metopar(paracetamol) when ever pain is too much.i am nit taking sibelum now but i am taking metopar when ever required.so i want a homeopathy consultatation if it can be cured by homeopathy or the level of headache can be lowered. Currently i face headache once in a week and i had to take metopar. Kindly suggest. My weight 80 kg And i am taking some neuro medicines ( stalopam 10, amitone 10) I also have cholesterol and taking (atorec 20)

Dr. Faran Siddiqui

Homeopathy

Migraine and headache are two different things migraine is primarily headache of one side in symmetrically

Some time at a sudden Strong half headache pain in left side and also left eye tearing Please consult me

Dr. Pushkar Mani

Physician

it could be migraine

FAQs

Naprosafe D Tablet

What is Naprosafe D 250 Tablet?

Naprosafe D 250 Tablet is a combination of two medicines: Naproxen and Domperidone. This combination helps in relieving the symptoms of migraine like headache, nausea and vomiting. Naproxen is a pain-killer that blocks the release of certain chemical messengers that cause headache. Domperidone is an anti-emetic agent (prokinetic). It increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This helps in relieving vomiting.

Can I stop taking Naprosafe D 250 Tablet when my migraine symptoms are relieved?

No, do not stop taking Naprosafe D 250 Tablet until advised by your doctor.

Can the use of Naprosafe D 250 Tablet cause diarrhea?

Yes, the use of Naprosafe D 250 Tablet can cause diarrhea. In case, you experience diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and you notice any signs of dehydration, like less urination with dark coloured and strong-smelling urine. Do not take any other medicine without consulting a doctor.

Are there any specific contraindications associated with the use of Naprosafe D 250 Tablet?

The use of Naprosafe D 250 Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.

Can the use of Naprosafe D 250 Tablet cause damage to kidneys?

Yes, the long-term use of Naprosafe D 250 Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lower the levels of prostaglandins in the body, which leads to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Can I take a higher than the recommended dose of Naprosafe D 250 Tablet?

No, taking a higher than the recommended dose of Naprosafe D 250 Tablet can increase the risks of side effects. If you are experiencing increased severity of migraine attacks which are not relieved by the recommended doses, please consult your doctor for re-evaluation.

What are the recommended storage conditions for Naprosafe D 250 Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Naproxen. Nutley, New Jersey: Roche Laboratories Inc. [Accessed 22 Apr. 2019] (online) Available from:
Domperidone and domperidone maleate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2003 [revised 14 Nov. 2017]. [Accessed 24 Jan. 2019] (online) Available from:
Drugs.com. Naproxen. [Accessed 22 Apr. 2019] (online) Available from:
Drugs.com. Domperidone. [Accessed 22 Apr. 2019] (online) Available from:

Marketer details

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Address: Plot No 315, Industrial Area Phase-2, Panchkula Haryana)-134109

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.