Itrafol Capsule belongs to a group of medicines called antifungals. It works by stopping the growth of fungi and is used to treat infections of the mouth, throat, vagina, and other parts of the body including fingernails and toenails. It kills fungi by destroying the fungal cell membrane.

Itrafol Capsule is used in treating various fungus infections

Uses of Itrafol Capsule

Treatment of Fungal infections

Benefits of Itrafol Capsule

In Treatment of Fungal infections

Itrafol Capsule is an antifungal medicine. It is used to treat infections in different parts of the body caused by fungi. It works by killing and stopping the growth of fungi. This provides relief from various symptoms caused by the infection and speeds up the healing process. You should keep taking the medicine until you complete the dose even if you get better. This will prevent the infection from returning.

Side effects of Itrafol Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Itrafol

Nausea
Abdominal pain
Constipation
Dizziness
Headache
Indigestion
Vomiting

How to use Itrafol Capsule

Take this medicine in the dose and duration as advised by your doctor. Itrafol Capsule is to be taken with food.

How Itrafol Capsule works

Itrafol Capsule is an antifungal medication. It kills fungi by destroying the fungal cell membrane. This treats your skin infection.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Itrafol Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Itrafol Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Itrafol Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Itrafol Capsule may cause side effects which could affect your ability to drive.
Itrafol Capsule can sometimes cause dizziness, blurred/double vision or hearing loss. This may affect your ability to drive.

Kidney

CAUTION

Itrafol Capsule should be used with caution in patients with kidney disease. Dose adjustment of Itrafol Capsule may be needed. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Itrafol Capsule in patients with liver disease. Please consult your doctor.
Inform your doctor if you develop signs of jaundice like yellowing of eyes and skin, itching, and clay colored stools while taking this medicine.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Itrafol Capsule

₹8.5/Capsule

Itrasys 100 Capsule

Systopic Laboratories Pvt Ltd

₹9.75/capsule

15% costlier

Fungikem 100 Capsule

Alkem Laboratories Ltd

₹14.29/capsule

68% costlier

Canditral 100 Capsule

Glenmark Pharmaceuticals Ltd

₹12.3/capsule

45% costlier

Syntran Capsule

Glenmark Pharmaceuticals Ltd

₹19.4/capsule

128% costlier

Itrason Capsule

Unison Pharmaceuticals Pvt Ltd

₹8/capsule

6% cheaper

View all substitutes

Quick tips

Itrafol Capsule helps treat fungal infections of mouth, skin, vagina or any other parts of the body.
Do not skip any doses and finish the full course of treatment even if you feel better.
Take it with food, preferably at the same time everyday.
Use a reliable method of contraception to prevent pregnancy while taking this medicine.
Do not take indigestion remedies (antacids) within 2 hours of taking Itrafol Capsule.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Inform your doctor if you develop allergic reactions, nerve pain, or hearing loss.

Fact Box

Chemical Class

Azoles {Triazoles}

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Fungal ergosterol synthesis inhibitor

Patient concerns

Medicine for fungal infections.

Dr. Atul Jain

Dermatology

There is hundred type of fungal infectionFrom which you sufferBetter visit clinic for proper examination

Fungal infections on body & face

Dr. Atula Gupta

Dermatology

Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks.Sertacide Cream for application twice daily for 1 month.Send pictures for better diagnosis and treatment

FAQs

What is Itrafol Capsule used for?

Itrafol Capsule is used to treat fungal infections caused by Trichophyton spp., Microsporum spp., and Epidermophyton floccosum. The infections caused could be ringworm infection, infection of the feet, or infection in the groin and buttocks. This medicine also treats persistent infection of fingernails and toenails, persistent candida (yeast) infections of vagina or candida (yeast) infections of the mouth or throat in patients with lower disease resistance. It is also used in the treatment of cryptococcal infection and infections caused by Histoplasma, aspergillus, and Blastomyces.

For how long do I need to take Itrafol Capsule?

The dose and length of treatment depends on the type and site of infection and your response to the treatment. For example, if you are taking Itrafol Capsule for athlete’s foot (fungal infection of the skin on the feet and between the toes), the dose may need to be taken for 30 days, on the other hand, if you are taking it for candidal infection of the vagina, the dose may span from 1 day to 3 days depending on the dosage advised by the doctor.

I am taking Itrafol Capsule for nail infection but there does not seem to be any improvement. Can I stop taking it?

No, you should not stop taking Itrafol Capsule without completing the entire course because doing so may not completely cure the fungal infection. It usually takes about 6-9 months for nail lesions to disappear because after the medicine eliminates the fungus, the new nail takes several months to grow. Do not worry if you do not see any improvement during the treatment.

Why has my doctor asked me to get blood tests done?

Your doctor is probably trying to monitor your liver’s functioning. Itrafol Capsule may cause serious liver damage. Therefore, if you develop loss of appetite, nausea, vomiting, dark urine, or abdominal pain while taking Itrafol Capsule, you should tell your doctor immediately.

Can I take antacid and Itrafol Capsule together?

Itrafol Capsule can be utilized by the body if there is sufficient acid in the stomach. Medicines for stomach ulcers, heartburn, or indigestion neutralize the acid produced by the stomach. Therefore, take antacids or any such medicine about 2 hours after taking Itrafol Capsule. If you are taking antacids (medicines that stop the production of stomach acid), take Itrafol Capsule capsules with a drink of cola.

What is drug resistance? Is it possible to develop resistance to Itrafol Capsule?

Sometimes it happens that the fungi get modified in your body and the medicine no longer works. This is called drug resistance. Resistance to Itrafol Capsule has been reported with some candida species (krusei, glabrata, and tropicalis). Itrafol Capsule should not be used for infection caused due to these species. Take the complete course of Itrafol Capsule to avoid drug resistance.

I have been on alprazolam for quite some time. Is it okay if I start Itrafol Capsule now?

Yes, you can take both Alprazolam and Itrafol Capsule together, but keep a watch on the side effects of alprazolam such as lightheadedness or drowsiness. If side effects appear after taking Itrafol Capsule, talk to your doctor who will modify the dose of alprazolam.

My doctor prescribed Itrafol Capsule to me but not to my friend who had a similar fungal infection because she was on dofetilide. Why is it so?

Your doctor did not prescribe Itrafol Capsule to your friend because Itrafol Capsule interferes with the working of dofetilide. This interference can cause disturbed electrical activity of the heart, which can be harmful to the patient.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1576-79.
Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 839-40.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 749-51.
Itraconazole. Turnhout, Belgium: Sanico N.V.; 1992 [revised Apr. 2010]. [Accessed 29 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:
New Zealand Data Sheet. Itrazole. Aukland, new Zealand: Viatris Ltd.; 2022. [Accessed 07 Jul. 2023]. (online) Available from:
Kurn H, Wadhwa R. Itraconazole. [Updated 2023 Apr 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 07 Jul. 2023]. (online) Available from:

Marketer details

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Address: 1310/A, Mondeal Heights, Nr Wide Angle Cinema, Sg Road, Ahmedabad - 380015, Gujarat, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.