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Author Details
Written By
Dr. Anuj Saini 2
MMST, MBBS
Reviewed By
Dr. Varun Gupta
MD Pharmacology, MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Irinot 100mg Injection

Prescription Required

Product introduction

Irinot 100mg Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells.

Irinot 100mg Injection is used to treat various types of cancer

Uses of Irinot Injection

Benefits of Irinot Injection

In Cancer of colon and rectum

Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Irinot 100mg Injection treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Irinot Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Irinot

  • Fatigue
  • Nausea
  • Vomiting
  • Weakness
  • Hair loss
  • Fever
  • Anemia (low number of red blood cells)
  • Diarrhea
  • Decreased white blood cell count (neutrophils)
  • Decreased appetite
  • Mucosal inflammation

How to use Irinot Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Irinot 100mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Irinot 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Irinot 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Irinot 100mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Irinot 100mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Irinot 100mg Injection may not be needed in these patients. Please consult your doctor.
Use of this medicine is not recommended for patients on dialysis.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Irinot 100mg Injection in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Irinot 100mg Injection
₹4100.0/Injection
Irinotel 100mg Injection
Fresenius Kabi India Pvt Ltd
₹948.29/injection
77% cheaper
Irnocel 100mg Injection
Celon Laboratories Ltd
₹4095/injection
same price
Irinotraz 100mg Injection
Alkem Laboratories Ltd
₹4500/injection
10% costlier
Intensic 100mg Injection
Neon Laboratories Ltd
₹518.82/injection
87% cheaper
Iretrol-Taj 100mg Injection
Taj Pharma India Ltd
₹4200/injection
2% costlier

Quick tips

  • Irinot 100mg Injection is used in combination with other medicines for the treatment of metastatic cancer of the colon and rectum.
  • It is given via a drip into a vein (intravenous infusion).
  • It may cause dizziness and visual disturbances. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Your doctor may get regular blood tests done to monitor your blood cells, kidney and liver function during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
  • Inform your doctor if you notice passage of blood in stools or experience dizziness or faintness, continuous episodes of nausea, vomiting, diarrhea or fever.

Fact Box

Chemical Class
Camptothecin Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Topoisomerase Inhibitor

Patient concerns

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    Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

    References

    1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 951.
    2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 736-37.
    3. Irinotecan hydrochloride trihydrate. Sandwich, Kent: Pfizer Limited; 1995 [revised May 2018]. Accessed 26 Jan. 2019] (online) Available from:External Link
    4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Irinotecan. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:External Link
    5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:External Link

    Marketer details

    Name: Khandelwal Laboratories Pvt Ltd
    Address: KHANDELWAL LABORATORIES PVT. LTD, 79/87 D.LADPATH, MUMBAI 400 033, INDIA
    Country of origin: India
    MRP
    ₹4100
    Inclusive of all taxes
    5.0 ml in 1 vial
    SOLD OUT
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