Glinil Tablet

Glibenclamide (5mg)

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Glinil Tablet is a medicine used to treat type 2 diabetes mellitus in adults. It belongs to a group of medicines called sulfonylureas and helps control blood sugar levels in people with diabetes. This helps to prevent serious complications of diabetes like kidney damage and blindness.

Written By Dr. Betina Chandolia, MDS, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 12 Nov 2024 | 01:11 AM (IST)

Gurgaon

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General Information

Contains

Glibenclamide (5mg)

Marketer

Cipla Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Glinil Tablet may be used by itself or along with other medicines. It should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking this medicine include nausea, headache, and dizziness. It can also sometimes cause low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking, and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Some people may find that they put on weight with this medicine.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Glinil Tablet

Type 2 diabetes mellitus

Side effects of Glinil Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Glinil

Hypoglycemia (low blood glucose level)
Nausea
Headache
Dizziness

How to use Glinil Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glinil Tablet is to be taken with food.

How Glinil Tablet works

Glinil Tablet is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.

All substitutes for Glinil Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
Be careful while driving or operating machinery until you know how Glinil Tablet affects you.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Glinil Tablet helps decrease high blood sugar level and avoid long-term complications of diabetes.
Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
Monitor your blood sugar level regularly while you are taking this medicine.
Be careful while driving or operating machinery until you know how Glinil Tablet affects you.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Glinil Tablet.

Pregnancy

SAFE IF PRESCRIBED

Glinil Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Glinil Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Monitor the breastfed baby’s blood sugar during treatment with Glinil Tablet

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

UNSAFE

Glinil Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.

Liver

CAUTION

Glinil Tablet should be used with caution in patients with liver disease. Dose adjustment of Glinil Tablet may be needed. Please consult your doctor.
Use of Glinil Tablet is not recommended in patients with severe liver disease. They can experience very low blood sugar levels while taking this medicine.

Interaction with drugs

Taking Glinil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Nilotinib (Oral Route)

If used together, Nilotinib may interrupt the efficacy of Glibenclamide.

Moderate

Chlorthalidone Test sha (Oral Route)

If taken in high doses, Chlorthalidone Test sha may increase blood glucose levels thereby reducing antidiabetic effect of Glibenclamide.

Moderate

Fluvastatin (Oral Route)

Fluvastatin may fasten the elimination of Glibenclamide leading to reduced efficacy. Library explanation 98

Moderate

Hydrochlorothiazide (Oral Route)

If taken in high doses, Hydrochlorothiazide may increase blood glucose levels thereby reducing antidiabetic effect of Glibenclamide.

Moderate

Indapamide (Oral Route)

If taken in high doses, Indapamide may increase blood glucose levels thereby reducing antidiabetic effect of Glibenclamide.

Frequently asked questions

Is Glinil Tablet the same as Glipizide?

No, Glinil Tablet and Glipizide are different medicines. However, they belong to the same class of medicines called sulfonylureas and are used to treat type 2 diabetes mellitus in adults.

Does Glinil Tablet play any role in the treatment of polycystic ovarian syndrome (PCOS)?

No, Glinil Tablet is not known to have any role in the treatment of polycystic ovarian syndrome (PCOS). Also, there is no clinical evidence available regarding the same.

Why should Glinil Tablet be used cautiously in elderly patients?

Glinil Tablet should be used with extra caution in elderly patients because they are at high risk of getting low blood sugar (hypoglycemic event).

Is Glinil Tablet useful in the management of prediabetes?

Glinil Tablet is not used for the management of prediabetes, a condition with blood glucose levels higher than normal but not high enough to label you as diabetic. There are clinical studies available, but the evidence is not strong enough for its use in prediabetes.

How is Glinil Tablet different from Teneligliptin?

Both Glinil Tablet and Teneligliptin are antidiabetic medicines and control blood sugar levels effectively. However, they work in different ways and may show different kinds of side effects. Glinil Tablet commonly causes hypoglycemia and weight gain while Teneligliptin causes headache and nasopharyngitis. Teneligliptin causes hypoglycemia when used along with insulins or sulfonylureas and does not cause weight gain.

Can I skip Glinil Tablet for a few days?

No, Glinil Tablet should not be skipped as it can make your diabetes worse. If you miss the dose by mistake, take it as soon as you remember.

Can I take Glinil Tablet if I have a sulfa allergy?

Use of Glinil Tablet should be avoided if you are allergic (hypersensitive) to sulfonylureas or sulfonamides or any of the other ingredients of this medicine.

Does Glinil Tablet cause weight gain?

Yes, Glinil Tablet can cause weight gain. It is advisable to closely monitor your diet and exercise regularly while taking this medicine. Avoid skipping your meals as it can cause very low blood sugar levels and you may end up snacking or taking a lot of sugars.

Is there any benefit of taking Glinil Tablet with insulin?

Glinil Tablet, when used with insulin, can help to control high blood sugar levels. Taking them together can help to lower the dose of insulin but there could also be an increased risk of hypoglycemia (low blood sugar levels). The dose of these medicines may need to be adjusted along with regular blood sugar level monitoring. Please consult your doctor if you have any doubts and follow your doctor's instructions carefully to get maximum benefit of Glinil Tablet.

Is it safe to take Glinil Tablet with Liraglutide?

Yes, Glinil Tablet and Liraglutide can be taken together, as they can help in better control of blood sugar levels. However, the risk of low blood sugar levels (hypoglycemia) can increase. Consult your doctor as a dose adjustment of the two may be needed.

Is Glinil Tablet a Thiazolidinedione?

No, Glinil Tablet is not a Thiazolidinedione, it is a sulfonylurea. However, both are antidiabetic medicines but belong to a different group of medicines.

Is Glinil Tablet useful in the management of gestational diabetes?

The use of insulin is advised during pregnancy to control the blood glucose levels. Insulin injections are the standard medication for gestational diabetes. Glinil Tablet may be advised as an alternative or in addition to insulin for the management of gestational diabetes. However, do not start taking Glinil Tablet until prescribed by the doctor.

Does Glinil Tablet cause hair loss?

No, hair loss is not seen with the use of Glinil Tablet. However, diabetes can lead to hair loss. Talk to your doctor if you have excessive hair loss as it could be due to some other underlying condition or it could be a sign of your diabetes getting worsened.

Is it safe to take Glinil Tablet with pioglitazone?

Yes, it is safe to take Glinil Tablet with Pioglitazone in patients with diabetes mellitus. Together these two medicines can control your blood sugar levels, lower plasma lipid levels and improve blood pressure. However, the risk of very low blood sugar levels can increase and the dose of these medicines may need to be adjusted.

Fact Box

Chemical Class

Second-generation sulfonylurea derivative

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Sulfonylureas (Insulin Secretagogues)

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1255.
Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 739-40.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 634-36.
DailyMed. Glibenclamide [Prescription Drug Label]. Guangdong Province, P.R. China: Pharmadax Inc.; 2016. [Accessed 20 Jan. 2022] (online) Available from:
Glibenclamide [Product Monograph]. Mirabel, Canada: Ratiopharm Inc.; 2006. [Accessed 20 Jan. 2022] (online) Available from:
Glibenclamide [FDA Prescribing Information]. Bridgewater NJ: Sanofi-Aventis; 2009. [Accessed 20 Jan. 2022] (online) Available from:
Glibenclamide [FDA Prescribing Information]. New York, NY; Pharmacia & Upjohn Company; 2010. [Accessed 20 Jan. 2022] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Glinil Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Glinil Tablet

Side effects of Glinil Tablet

How to use Glinil Tablet

How Glinil Tablet works

All substitutes for Glinil Tablet

Getrol 5mg Tablet

Glybovin 5 Tablet

Glibet 5mg Tablet

Diachek 5mg Tablet

Aviglen 5mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Nilotinib (Oral Route)

Chlorthalidone Test sha (Oral Route)

Fluvastatin (Oral Route)

Hydrochlorothiazide (Oral Route)

Indapamide (Oral Route)

Frequently asked questions

Is Glinil Tablet the same as Glipizide?

Does Glinil Tablet play any role in the treatment of polycystic ovarian syndrome (PCOS)?

Why should Glinil Tablet be used cautiously in elderly patients?

Is Glinil Tablet useful in the management of prediabetes?

How is Glinil Tablet different from Teneligliptin?

Can I skip Glinil Tablet for a few days?

Can I take Glinil Tablet if I have a sulfa allergy?

Does Glinil Tablet cause weight gain?

Is there any benefit of taking Glinil Tablet with insulin?

Is it safe to take Glinil Tablet with Liraglutide?

Is Glinil Tablet a Thiazolidinedione?

Is Glinil Tablet useful in the management of gestational diabetes?

Does Glinil Tablet cause hair loss?

Is it safe to take Glinil Tablet with pioglitazone?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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