

Estofert Tablet
Estradiol (2mg)
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Estofert Tablet is a female sex hormone (estrogen). This is a type of hormone replacement therapy (HRT) that is used to treat symptoms associated with menopause (hot flushes, vaginal dryness, and itching), estrogen deficiency, and thinning of bones (osteoporosis).
Written By Dr. Betina Chandolia, MDS, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 12 Nov 2024 | 01:05 AM (IST)
Written By Dr. Betina Chandolia, MDS, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 12 Nov 2024 | 01:05 AM (IST)
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General Information
The content is shown in English



Product introduction
Estofert Tablet is to be swallowed with water. It can be taken with or without food, but remember to take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.
The most common side effects of this HRT are headaches, breast pain, irregular vaginal bleeding or spotting, abdominal cramps or bloating, nausea, vomiting, and hair loss. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs, etc.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.
The most common side effects of this HRT are headaches, breast pain, irregular vaginal bleeding or spotting, abdominal cramps or bloating, nausea, vomiting, and hair loss. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs, etc.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.
Uses of Estofert Tablet
Benefits of Estofert Tablet
Hormone replacement therapy
Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Estrogen is one of two important hormones (the other is progesterone) used in this treatment. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Estrogen is one of two important hormones (the other is progesterone) used in this treatment. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
Side effects of Estofert Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Estofert
- Headache
- Nausea
- Breast pain
- Abdominal cramp
- Bloating
- Vaginal spotting
- Vomiting
How to use Estofert Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Estofert Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Estofert Tablet works
Estofert Tablet contains a medication called estrogen (female sex hormone). It works by replacing estrogen that is normally produced by the body. In women who are undergoing or have attained menopause, it prevents symptoms such as hot flushes, vaginal burning, dryness, and itching, caused due to lack of estrogen.
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For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- You have been prescribed Estofert Tablet as a part of hormone replacement therapy to relieve symptoms of menopause.
- It may also be used for preventing osteoporosis in postmenopausal women who are at high risk of fractures.
- Take it at the same time everyday to help you remember to take it.
- Inform your doctor if you experience any unusual vaginal bleeding or spotting, abnormal vaginal discharge or vaginal discomfort while taking Estofert Tablet.
- It may increase the risk of breast cancer. Have regular breast examinations.
- Stop taking this medicine and inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, or changes in vision. These could be symptoms of a blood clot in a vein.
Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Estofert Tablet. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Estofert Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
UNSAFE
Estofert Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving
SAFE
Estofert Tablet does not usually affect your ability to drive.

Kidney
CAUTION
Estofert Tablet should be used with caution in patients with kidney disease. Dose adjustment of Estofert Tablet may be needed. Please consult your doctor.

Liver
CAUTION
Estofert Tablet should be used with caution in patients with liver disease. Dose adjustment of Estofert Tablet may be needed. Please consult your doctor.
Use of Estofert Tablet is not recommended in patients who previously had liver disease and the liver function tests are still not normal and should not be given to women with severe hepatic disease.
Use of Estofert Tablet is not recommended in patients who previously had liver disease and the liver function tests are still not normal and should not be given to women with severe hepatic disease.
Interaction with drugs
Taking Estofert with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate
Tranexamic Acid (Oral Route)
Concurrent use may increase the risk of undesired clotting in blood vessels. This may increase the risk of heart attack or stroke.
Moderate
Tranexamic Acid (Injection Route)
Concurrent use may increase the risk of undesired clotting in blood vessels. This may increase the risk of heart attack or stroke.
Frequently asked questions
Estofert Tablet contains Estradiol, which is an estrogen hormone. It helps in treating estrogen deficiency symptoms like hot flushes (red and warm face) and vaginal dryness in women. It is also used to prevent osteoporosis (thinning and weakening of bones) in postmenopausal women, who are at high risk of fractures and have limited treatment choice.
If you miss a dose, you should take it as soon as possible. If the dose was missed by more than 12 hours, you should not take the missed dose and simply continue the usual dosing schedule.
The common side effects associated with Estofert Tablet are lower abdominal pain, periods pain, breast tenderness, endometrial hyperplasia (thickening of uterus lining) and vaginal discharge. Most of these symptoms are temporary. However, if these persist, check with your doctor as soon as possible.
For estrogen deficiency, treatment is based on the underlying cause. Your doctor may choose from a variety of medications depending upon your age and clinical conditions. The medications will also depend upon whether you are estrogen deficient or have high progesterone levels.
Estofert Tablet should not be taken by patients who have unusual vaginal bleeding, liver problems, or bleeding disorder. It should also be avoided to patients who are pregnant or are allergic to Estofert Tablet. Patients who have had uterus or breast cancer, had a stroke or heart attack, or currently have or had blood clots should also avoid this medicine.
Estofert Tablet may cause either weight gain or weight loss. This is a common side effect of Estofert Tablet. However, exercising regularly and eating a healthy nutritious diet can help you prevent weight gain. In case you notice weight gain and it bothers you, consult your doctor.
Estofert Tablet tablets should be taken exactly as advised by your doctor. Swallow the tablets whole with water. You can take it at any time of the day but take it at the same time each day.
Fact Box
Chemical Class
Estradiol Congeners
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Estrogens
References
- Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1173-75.
- Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 701-702.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 500-501.
- MedIndia. Estradiol. [Accessed 03 Apr. 2019] (online) Available from:
- Estradiol. Rockaway, New Jersey: Warner Chilcot; 2009. [Accessed 03 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 01 Apr. 2019] (online) Available from:
- CiplaMed. Estradiol valerate [Prescribing Information]. [Last Revised: February 2021]. [Accessed 24 June 2023]. (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Gufic Bioscience Ltd
Address: 37,1st Floor, Kamala Bhavan II, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (INDIA)
Address: 37,1st Floor, Kamala Bhavan II, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (INDIA)
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Estofert Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Estofert Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- Complete Blood Count
- Glucose - Fasting
- Thyroid profile Total
- Glycosylated Hemoglobin
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-OH)
- Urine Routine & Microscopy
- Coronavirus Covid-19 Test (RT-PCR technique)
- Liver Function Test
- Kidney Function Test
- Thyroid Stimulating Hormone, Ultrasensitive
- Erythrocyte Sedimentation Rate
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Calcium
- Creatinine
- Diabetes Screening
- Kidney Function Test with Electrolytes
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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