Espazine 1mg Injection

Trifluoperazine (1mg)

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Espazine 1mg Injection is used in the treatment of schizophrenia. It alters the thoughts and elevates the mood, improving the person’s ability to think, feel, and behave.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS,
Last updated on 12 Nov 2024 | 01:11 AM (IST)

MRP ₹28.1

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General Information

Contains

Trifluoperazine (1mg)

Marketer

Glaxo SmithKline Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Espazine 1mg Injection is given as an injection under the supervision of a healthcare professional and should not be self-administered. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this injection include dry mouth, abnormality of voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine can lead to weight gain, have a healthy balanced diet, and exercise regularly. You may also notice some injection site reactions such as pain, redness, or swelling. However, these are temporary and usually resolve on their own. Please consult your doctor in case these do not subside or bother you.

Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

Uses of Espazine Injection

Treatment of Schizophrenia

Benefits of Espazine Injection

Treatment of Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings, and behavior become abnormal. Espazine 1mg Injection helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Side effects of Espazine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Espazine

Orthostatic hypotension (sudden lowering of blood pressure on standing)
Sleepiness
Dryness in mouth
Abnormality of voluntary movements
Weight gain
Increased prolactin level in blood
Urinary retention
Constipation
Muscle stiffness
Tremors
Injection site reactions (pain, swelling, redness)

How to use Espazine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Espazine Injection works

Espazine 1mg Injection is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

Quick tips

You have been prescribed Espazine 1mg Injection for the treatment of schizophrenia.
It may cause less weight gain as compared to other similar medicines.
Use caution while driving or doing anything that requires concentration as Espazine 1mg Injection can cause dizziness and sleepiness.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Avoid drinking alcohol while taking this medicine as it can cause increased sedation.
Inform your doctor if you experience abnormal movements, particularly of the face, lips, jaw and tongue, while taking this medicine.
It may increase your blood sugar and cholesterol level. Eat healthy, exercise regularly and monitor your blood levels regularly.
Don't stop taking Espazine 1mg Injection without talking to your doctor first as it may cause worsening of symptoms.

Safety advice

Alcohol

UNSAFE

Espazine 1mg Injection may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Espazine 1mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Espazine 1mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Espazine 1mg Injection may cause side effects which could affect your ability to drive.
Espazine 1mg Injection make u feel dizzy, drowsy or can cause blurred vision. This may affect your driving ability.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Espazine 1mg Injection in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Espazine 1mg Injection in patients with liver disease. Please consult your doctor.
However, the use of Espazine 1mg Injection is not considered safe in patients with liver disease as per the available data.

Interaction with drugs

Taking Espazine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Mild

Ramipril (Oral Route)

Concurrent use may cause a drop in blood pressure while standing. You may experience dizziness, weakness, and blurred vision.

Mild

Metoprolol Succinate (Oral Route)

Although the likelihood is low, concurrent use may cause low blood pressure.

Fact Box

Chemical Class

Phenothiazine Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Typical Antipsychotics

References

Stahl SM, editor. Trifluoperazine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 691-95.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1404.
Drugs.com. Trifluoperazine. [Accessed 19 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Trifluoperazine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd
Address: Dr. Annie Besant Road, Mumbai - 400 030

Vendor Details

Country of origin: India

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Espazine 1mg Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Espazine Injection

Benefits of Espazine Injection

Side effects of Espazine Injection

How to use Espazine Injection

How Espazine Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Ramipril (Oral Route)

Metoprolol Succinate (Oral Route)

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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