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MD Pharmacology, MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Endoprost 250 Injection

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Endoprost 250 Injection is a medicine used to control excessive bleeding from the uterus, that may occur after the childbirth. It stimulates contraction of the uterine muscles thus, helps to control post-delivery bleeding.

Endoprost 250 Injection is used to stop excessive bleeding in women who have just given birth, when bleeding is due to the womb failing to return to its normal size.

Uses of Endoprost Injection

  • Post-delivery bleeding

Benefits of Endoprost Injection

In Post-delivery bleeding

Endoprost 250 Injection helps to control excessive bleeding after giving birth. This helps to prevent severe loss of blood that can lead to dropping of blood pressure, shock and even death if not controlled in time. It helps proper contraction of the uterus and therefore prevents hemorrhage and further complications.

Side effects of Endoprost Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Endoprost

  • Vomiting
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Headache
  • Nausea
  • Chills
  • Diarrhea
  • Placental retention
  • Cough

How to use Endoprost Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Endoprost 250 Injection. Please consult your doctor.
Pregnancy
UNSAFE
Endoprost 250 Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CAUTION
Endoprost 250 Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
UNSAFE
Endoprost 250 Injection may cause side effects which could affect your ability to drive.
As Endoprost 250 Injection may make you lose consciousness, feel dizzy or drowsy and this may affect your ability to drive
Kidney
CAUTION
Endoprost 250 Injection should be used with caution in patients with kidney disease. Dose adjustment of Endoprost 250 Injection may be needed. Please consult your doctor.
Use of Endoprost 250 Injection is not recommended in patients with active kidney disease.
Liver
CAUTION
Endoprost 250 Injection should be used with caution in patients with liver disease. Dose adjustment of Endoprost 250 Injection may be needed. Please consult your doctor.
Use of Endoprost 250 Injection is not recommended in patients with active liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Endoprost 250 Injection
₹144.0/Injection
Caboprost 250mcg Injection
Neon Laboratories Ltd
₹232.8/injection
62% costlier
Cystos 250mcg Injection
Vhb Life Sciences Inc
₹675/injection
369% costlier
Evacarb 250mcg Injection
Celon Laboratories Ltd
₹119/injection
17% cheaper
₹151/injection
5% costlier
Prostodin 250mcg Injection
Zydus Healthcare Limited
₹161.2/injection
12% costlier

Quick tips

  • Endoprost 250 Injection increases the contraction of your womb which helps to control excessive bleeding after delivery.
  • It is injected deep in to a muscle by your doctor or nurse.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • It may cause an increase in body temperature. This will return to normal few hours after the last injection.
  • Inform your doctor if you have problems with your heart, lung, kidney or liver.

Fact Box

Chemical Class
Prostaglandin Derivative
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Methyl-PGF2α analogue

Patient concerns

arrow
Lower back pain post delivery.
Dr. Akshat Goel
Orthopaedics
Do Hot fomentation and Apply Dynapar QPS spray Take Tab Myospas-D twice daily and Cap Nurokind-Gold twice daily and Cap Pansec-DSR once daily empty stomach for 4 days
Post delivery lots of illness
Dr. Pushkar Mani
Physician
Kindly refer to gyanecologist
arrow

FAQs

What is Endoprost 250 Injection and what is it used for?

Endoprost 250 Injection is an injectable preparation which contains Carboprost. It is used to control excessive bleeding from the uterus that may occur after childbirth. It is used only when other methods or medicines fail to work. It may also be used in the medical abortion of pregnancy between 13th and 20th weeks of gestation.

How and in what dose can it be used?

It is given as an injection, only at a hospital or clinic by the medical healthcare professional. The dose is decided by the doctor, depending on the severity of bleeding after delivery.

What may be the possible side effects associated with it?

The most common side effects include vomiting, nausea, diarrhea, flushing, and headache. You may also feel increased uterine contractions, for some time. However, these conditions are manageable in hospital settings.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 208-209.
  2. Medscape. Carboprost. [Accessed 03 Apr. 2019] (online) Available from:External Link
  3. Carboprost tromethamine. New York, New York: Pharmacia & Upjohn Co.; 2013. [Accessed 06 Feb. 2019] (online) Available from:External Link
  4. Carboprost. Sandwich, Kent: Pfizer Limited; 1996 [revised Oct. 2013]. [Accessed 03 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Bharat Serums & Vaccines Ltd
Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.
Country of origin: India

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