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Doncorate 250mg Tablet ER
Valproic Acid (250mg)
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Doncorate 250mg Tablet ER is used to treat epilepsy (seizures) and bipolar disorder. It is also used in the prevention of migraines. It has a calming effect on the brain by relaxing the nerves.
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS,
Last updated on 08 Nov 2024 | 01:08 AM (IST)
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS,
Last updated on 08 Nov 2024 | 01:08 AM (IST)
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General Information
The content is shown in English



Product introduction
Doncorate 250mg Tablet ER may be taken with or without food, preferably at the same time, each day. Take this medicine in the dose and duration as advised by your doctor. If you have missed a dose, take it as soon as you remember it. Never skip any doses and finish the full course of treatment even if you feel better. Do not stop taking it abruptly without discussing it with your doctor, as it may increase seizure frequency.
Some of the common side effects of this medicine include headache, blurred vision, loss of appetite, nausea, vomiting, hair loss, and diarrhea. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain, and to control it, you should have a balanced diet and exercise regularly. Please consult your doctor if these side effects bother you or do not go away.
Some of the common side effects of this medicine include headache, blurred vision, loss of appetite, nausea, vomiting, hair loss, and diarrhea. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain, and to control it, you should have a balanced diet and exercise regularly. Please consult your doctor if these side effects bother you or do not go away.
Uses of Doncorate Tablet ER
Benefits of Doncorate Tablet ER
Epilepsy/Seizures
Doncorate 250mg Tablet ER is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.
Doncorate 250mg Tablet ER is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.
Prevention of Migraine
It is not fully established how Doncorate 250mg Tablet ER helps prevent migraines. It may change the abnormal and excessive activity of the nerve cells in the brain or increase the activity in a region of the brain associated with migraines. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.
It is not fully established how Doncorate 250mg Tablet ER helps prevent migraines. It may change the abnormal and excessive activity of the nerve cells in the brain or increase the activity in a region of the brain associated with migraines. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.
Bipolar disorder
Doncorate 250mg Tablet ER works to restore the normal balance of nerve activity in your brain. It can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of low mood. It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.
Doncorate 250mg Tablet ER works to restore the normal balance of nerve activity in your brain. It can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of low mood. It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.
Side effects of Doncorate Tablet ER
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Doncorate
- Headache
- Dizziness
- Blurred vision
- Loss of appetite
- Nausea
- Vomiting
- Sleepiness
- Hair loss
- Weight gain
- Tremors
- Double vision
- Diarrhea
- Impaired coordination
- Increased appetite
- Weakness
- Stomach pain
How to use Doncorate Tablet ER
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Doncorate 250mg Tablet ER is to be taken with food.
How Doncorate Tablet ER works
Doncorate 250mg Tablet ER is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.
All substitutes for Doncorate 250mg Tablet ER
For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
- Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
- Some healthy tips to prevent seizures:
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/laptop.
- Take your medication on time.
- It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
- It may cause cosmetic side effects such as increased hair growth on the face, acne and thinning of hair. Talk to your doctor if this bothers you.
- Monitor your weight during treatment with this medicine as it can cause weight gain.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
- Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Doncorate 250mg Tablet ER.

Pregnancy
CONSULT YOUR DOCTOR
Doncorate 250mg Tablet ER is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding
SAFE IF PRESCRIBED
Doncorate 250mg Tablet ER is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving
UNSAFE
Doncorate 250mg Tablet ER may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
CAUTION
Doncorate 250mg Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Doncorate 250mg Tablet ER may be needed. Please consult your doctor.
However, talk to your doctor if you have any underlying kidney disease.
However, talk to your doctor if you have any underlying kidney disease.

Liver
UNSAFE
Doncorate 250mg Tablet ER is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Use of Doncorate 250mg Tablet ER is not recommended in patients with severe liver disease and active liver disease.
Use of Doncorate 250mg Tablet ER is not recommended in patients with severe liver disease and active liver disease.
Frequently asked questions
Doncorate 250mg Tablet ER does not cure your condition, it only prevents the seizures from occurring. Therefore, you will have to keep on taking it, maybe for years. Consult your doctor if face any problems while taking this medicine.
You should not stop taking Doncorate 250mg Tablet ER suddenly. It should be discontinued gradually. Stopping it suddenly may increase the chances of recurrence of seizures. Always consult your doctor if you feel the need to stop taking this medicine.
Yes, weight gain can occur with the use of Doncorate 250mg Tablet ER. To control your weight, you should have a healthy balanced diet and exercise regularly. Talk to your doctor if you have any other concerns.
Yes, Doncorate 250mg Tablet ER does not have any effect on the working of birth control pills. However, contraceptives (birth control pills) may interfere with the working of Doncorate 250mg Tablet ER and seizures may occur. It is important that you inform your doctor that you are using birth control pills. Your doctor will keep a track on your response to the treatment and monitor the Doncorate 250mg Tablet ER levels in your blood levels.
Many patients can safely take Doncorate 250mg Tablet ER for a long time. Rarely, long-term use of Doncorate 250mg Tablet ER may weaken your bones, thereby increasing their chances of breaking easily (osteoporosis and osteopenia). If you are taking Doncorate 250mg Tablet ER for a long time, get regular check ups done for bone health.
Doncorate 250mg Tablet ER may cause thinning of hair, change of hair colour and even hair loss. If you are concerned talk to your doctor if it is possible to reduce the dose of Doncorate 250mg Tablet ER. Your hair may regrow after either reducing your dose or switching to a different medicine.
Fact Box
Chemical Class
Valproic Acid Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Sodium channel modulators (AED)
References
- McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 596-98.
- Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 413-15.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1449-54.
- Valporic acid. Barceloneta, PR :AbbVie LTD; 1978 [revised Feb 2016]. [Accessed 19 Mar 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Bondane Pharma
Address: OM Maa Plot,Nh-8, Opposite Dashrath Village, Dashrath Vadodara - 391740, Gujarat, India
Address: OM Maa Plot,Nh-8, Opposite Dashrath Village, Dashrath Vadodara - 391740, Gujarat, India
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Doncorate 250mg Tablet ER. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Doncorate 250mg Tablet ER. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- Complete Blood Count
- Glucose - Fasting
- Thyroid profile Total
- Glycosylated Hemoglobin
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-OH)
- Urine Routine & Microscopy
- Coronavirus Covid-19 Test (RT-PCR technique)
- Liver Function Test
- Kidney Function Test
- Thyroid Stimulating Hormone, Ultrasensitive
- Erythrocyte Sedimentation Rate
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Calcium
- Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- Kidney Function Test with Electrolytes
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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