Difin-Plus Tablet is a combination medicine that helps in relieving pain. It is used to relieve pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve fever, muscle pain, back pain, toothache, or pain in the ear and throat.

Difin-Plus Tablet is a combination of two medicines: Difin-Plus Tablet1 and Difin-Plus Tablet2.

Uses of Difin-Plus Tablet

Pain relief

Benefits of Difin-Plus Tablet

In Pain relief

Difin-Plus Tablet is a combination of two medicines that belong to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.

Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Difin-Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Difin-Plus

Nausea
Vomiting
Diarrhea
Increased liver enzymes

How to use Difin-Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Difin-Plus Tablet is to be taken with food.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Difin-Plus Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Difin-Plus Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Difin-Plus Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Difin-Plus Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CAUTION

Difin-Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment of Difin-Plus Tablet may be needed. Please consult your doctor.
Use of Difin-Plus Tablet is not recommended in patients with severe kidney disease.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Difin-Plus Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Difin-Plus Tablet?

If you miss a dose of Difin-Plus Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Difin-Plus Tablet

₹3.5/Tablet

Sumo Tablet

Alkem Laboratories Ltd

₹8.27/tablet

136% costlier

Nimsaid-P Tablet

Medley Pharmaceuticals

₹7.5/tablet

114% costlier

Nicip Plus Tablet

Cipla Ltd

₹6.27/tablet

79% costlier

Dolamide Tablet

Sun Pharmaceutical Industries Ltd

₹7.69/tablet

120% costlier

Nimprex-P Tablet

Seagull Pharmaceutical Pvt Ltd

₹2.8/tablet

20% cheaper

View all substitutes

Quick tips

Difin-Plus Tablet

You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

for body pain relief i taking dolokind - plus tablet I asking advise sir which is best for long time

Dr. Pushkar Mani

Physician

for long time no pain killer is goodfirst need to diagnose the reason of pain

I am getting pain in right arm at joint point at solder only when we take hand upward direction.

Dr. Pushkar Mani

Physician

could be frozen shoulder or injury to ligamentfor temp relief take aceclo Plus sos for pain

Dear Sir I m mental patient and I was taken megapose plus tablet but now gov. Banned this. So I want substitute tablet

Dr. Venkatraju Kalidindi

Psychiatry

Dear 1mg user, medicines gives quick relief and has side effects too so consult your doctor and see how to reduce dose and control totally, later you can take counselling that really helps you. Pay Rs 99 and call me on my phone www.dontfeel.com for counselling

FAQs

Difin-Plus Tablet

What is Difin-Plus Tablet?

Difin-Plus Tablet is a combination of two medicines: Nimesulide and Paracetamol. This medication helps in relieving the pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation.

Can I stop taking Difin-Plus Tablet when my pain is relieved?

Difin-Plus Tablet is usually used for short-term pain relief and can be discontinued if there is no pain. However, it should be continued if your physician has advised you to do so.

Can the use of Difin-Plus Tablet cause nausea and vomiting?

Yes, the use of Difin-Plus Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medicine. In case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Talk to your doctor if vomiting persists and you notice any signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.

Are there any specific contraindications associated with the use of Difin-Plus Tablet?

The use of Difin-Plus Tablet is considered to be harmful in patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). Its use should also be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with the history of heart failure, high blood pressure, and liver or kidney disease.

Can I take Difin-Plus Tablet with Vitamin B-complex?

Yes, Difin-Plus Tablet can be taken with Vitamin B-complex preparations. While Difin-Plus Tablet helps to relieve pain, Vitamin B-complex helps to correct the vitamin deficiency that might be causing your symptoms.

Does Difin-Plus Tablet help in relieving stomach pain?

No, Difin-Plus Tablet preferably should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.

Can the use of Difin-Plus Tablet cause damage to the liver?

Difin-Plus Tablet contains Nimesulide and Paracetamol and both these medicines are known to cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease.

Is it safe to take a higher than the recommended dose of Difin-Plus Tablet?

No, you should avoid taking a higher than the recommended dose of Difin-Plus Tablet as it can increase the risks of side effects. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.

What are the recommended storage conditions for Difin-Plus Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

European Medicine Agency. Nimesulide; 2004. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Nimesulide. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Nimesulide. [Accessed 02 Apr. 2019] (online) Available from:

Marketer details

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Address: Building No. 83, Fist Floor,Near SBI Bank, Baltana Road, Raipur Kalan, 160102, Chandigarh, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.