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Dexmedine Injection

Dexmedetomidine (100mcg)
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Dexmedine Injection is a prescription medicine used to provide sedation (a state of calm, drowsiness, or sleep) for adult patients in intensive care settings. It may also be used for awake sedation during diagnostic and surgical procedures.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS,
Last updated on 12 Nov 2024 | 01:06 AM (IST)
 
 
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Dexdine 100mcg Injection
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<span style='color:#626A7A'>Dexmedine Injection</span>
Dexmedine Injection
vial of 0.5 ml Injection
₹200
by Samarth Life Sciences Pvt Ltd
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Same composition
Dexdine 100mcg Injection
Dexdine 100mcg Injection
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Dexmedine Injection image
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Product introduction

Dexmedine Injection is given as an infusion (drip) into a vein under the supervision of a healthcare professional. It is important to inform your doctor if you are suffering from any medical conditions like slow heart rate, low blood pressure, neurological disorder, severe liver problems, or have ever developed a serious fever after some medicines, especially after taking anesthesia. Your doctor will monitor the cardiac and respiratory state after providing this injection.

Common side effects of this medicine include dryness in the mouth, decreased blood pressure, and slow heart rate. Consult your doctor if these side effects do not improve with time or worsen. They may be able to suggest ways to prevent or reduce the side effects.

Uses of Dexmedine Injection

  • Sedative

Benefits of Dexmedine Injection

Sedative
Dexmedine Injection helps to calm the activity of the nerves and helps induce a deep state of sleep called sedation. Therefore this medicine acts as a sedative and is used in intensive care units (ICUs) to provide relief to patients and to keep them stress-free. It can also be used to carry out some diagnostic or minor surgical procedures. It is given as an injection by a doctor or nurse in a hospital setup.

Side effects of Dexmedine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dexmedine
  • Dryness in mouth
  • Decreased blood pressure
  • Slow heart rate

How to use Dexmedine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Dexmedine Injection works

Dexmedine Injection works by modulating the action of certain chemical messengers in the brain that relieves pain and induces sleep.

Quick tips

  • Dexmedine Injection is given as an infusion into the veins by healthcare professionals only.
  • Your doctor will closely monitor your heart rate, blood pressure, breathing rate and oxygen level during the treatment.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

Alcohol

UNSAFE
Dexmedine Injection may cause excessive drowsiness with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Dexmedine Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Dexmedine Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

NOT RELEVANT
Not relevant, as Dexmedine Injection is intended for use in hospitalised patients.
Kidney

Kidney

SAFE IF PRESCRIBED
Dexmedine Injection is safe to use in patients with kidney disease. No dose adjustment of Dexmedine Injection is recommended.
Liver

Liver

CAUTION
Dexmedine Injection should be used with caution in patients with liver disease. Dose adjustment of Dexmedine Injection may be needed. Please consult your doctor.

Frequently asked questions

Dexmedine Injection is used to provide sedation (a state of calm, drowsiness, or sleep) for adult patients in intensive care settings (i.e. in initially intubated and mechanically ventilated patients or non-intubated patients prior to and/or during surgical and other procedures).
Dexmedine Injection is a sedative that belongs to a class of drugs called centrally active selective 2A agonists.It is not a controlled drug/substance
Yes, Dexmedine Injection approved by FDA
Dexmedine Injection is given as an infusion (drip) into veins. It may cause pain at the injection site and low heart rate (bradycardia). It does not cause amnesia.
Dexmedine Injection activates the central 2A receptors which causes sedation and analgesia.

Fact Box

Chemical Class

Imidazole Derivative

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Alpha 2-Adrenoceptor agonists (Anaesthetic)

References

  1. Stahl SM, editor. Dextromethorphan. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 181-83.
  2. Patel PM, Patel HH, Roth DM. General Anesthetics and Therapeutic Gases. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 548-49.
  3. Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 140, 145.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 381-82.
  5. Dexmedetomidine hydrochloride. Lake Forest, Illinois: Hospira, Inc.; 1999 [revised Jun. 2013]. [Accessed 12 Feb. 2019] (online) Available from:
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dexmedetomidine. [Updated 2018 Dec 3]. [Accessed 20 Feb. 2020] (online) Available from:
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Samarth Life Sciences Pvt Ltd
Address: Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.

Vendor Details

Country of origin: India
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