Desferal 500mg Injection is a medicine used in the treatment of chronic iron overload caused due to frequent blood transfusion. It helps in removing the excess iron from the body and reduces the risk of it causing organ damage.

Repeated blood transfusions in some patients can cause a build-up of excess iron. Desferal 500mg Injection is used to remove the excess iron from the body

Uses of Desferal Injection

Benefits of Desferal Injection

In Iron overload

Iron overload, as the name suggests, means excess of iron in the human body. Too much iron can cause organ damage, which can lead to conditions such as cancer, irregular heartbeat and cirrhosis of the liver. Symptoms are related to conditions that arise from iron overload such as high blood sugar levels (diabetes), darkening of the skin, abnormal heart rhythm or arthritis. By using Desferal 500mg Injection, this excess of iron can be decreased to safe levels by removing it from the body through stools. This helps to reduce the risk of organ damage and prevents further complications. Desferal 500mg Injection is given by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Desferal Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Desferal

Flushing (sense of warmth in the face, ears, neck and trunk)
Rash
Decreased blood pressure
Abdominal pain

How to use Desferal Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Desferal 500mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Desferal 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Desferal 500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Desferal 500mg Injection may cause side effects which could affect your ability to drive.
If you experience dizziness or other central nervous disturbances, or impairment of vision with the use of Desferal 500mg Injection then you should refrain from driving a vehicle.

Kidney

CAUTION

Desferal 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Desferal 500mg Injection may be needed. Please consult your doctor.
Use of Desferal 500mg Injection is not recommended in patients with severe kidney disease.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Desferal 500mg Injection in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

Desferal 500mg Injection is used to reduce excess iron from the body.
Desferal 500mg Injection may cause your urine to turn a red/brown color. This is the iron being removed from your body and is nothing for you to worry about as it is quite harmless.
If you are taking any antacid, take them 2 hours before or after Desferal 500mg Injection.
Desferal 500mg Injection may cause dizziness. It is advisable not to drive or operate any machinery until you feel normal again.
Inform your doctor if you have any liver or kidney disease.
Inform your doctor if you are pregnant or breastfeeding.

Fact Box

Chemical Class

Acetohydroxamic acids derivative

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Iron chelating agents

Patient concerns

Hello doctor I have thallassemia major since birth and due to iron overload of repetitive blood transfusion i have diagnosed with diabetes 3 yr ago -at the time of diabetes diagnosis my sugar level is 650 mg/dl. Now according to my case what could be the state of my diabetes type 1 or type 2 ?

Dr. Amit Modi

Paediatrics

Hello, Diabetes in thalassaemia is thought to be caused mainly by iron overload, from repeated blood transfusions, damaging the pancreas. Insulin secretion may be reduced, possibly because iron is directly toxic to the insulin producing pancreatic ?-cells. So it is type 1 DM .

Diabatic for last 5 years insulin dependent D Vitamin iron deficiency

Dr. Sanjay Bhatt

Physician

Hi you need to consult doctor nearby by.Or u can visit our clinic at sector 52 gurgaon in RDCITY snergy clinic. Diabetic pt should be in regular contact with the diabetologist or treating doctor. Do all regular tests and follow diet and exercise. Disease can be well controlled. A person can avoid diabetic complications.

Diabatic for last 4 years insulin dependent D Vitamin iron deficiency

Dr. Ila Jain Khandelwal

Pathology

Dear Sir Thank you for sharing your reports with me. It shows the following important things: 1. your iron level is low, for this you can have a diet rich in lots of iron like jaggery, spinach, leafy vegetables etc. Your vitamin D level is low, for this you can have calcirol sachet in milk once a week for at least 6 weeks. Your glycosylated hemoglobin and average blood glucose level is high, you should consult your doctor for this for the review of treatment.

H.B is just 7 gram not improving iron not suitable

Dr. Gopal Samdani

Paediatrics

Please consult Dr. will take detail history and will examine your child in detail. may ask you for blood test. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment.Just to give you idea i am giving examples of diseases where anemia is presentCongenital dyserythropoietic anemia Diamond-Blackfan anemia G-6-PD deficiency Hemophagocytic lymphohistiocytosis (HLH), congenital or acquired Iron refractory iron deficiency anemia (IRIDA) Nutritional iron deficiency Paroxysmal nocturnal hemoglobinuria Pure red cell aplasia Rheumatoid arthritis Sideroblastic anemia Unstable hemoglobinopathies Hookworm infection Hypothyroidism Myelodysplastic syndrome Myelofibrosis Systemic lupus erythematosus Thalassemia Thalassemia intermedia Pyruvate kinase deficiency

User feedback

Patients taking Desferal 500mg Injection

Once A Day

65%

Once A Month

10%

Once A Week

Alternate Day

Twice A Day

Four Times A *

Thrice A Day

*Four Times A Day

What are you using Desferal Injection for?

Transfusion d*

71%

Iron overload

29%

*Transfusion dependent thalassemia

How much was the improvement?

Excellent

83%

Average

17%

What were the side-effects while using Desferal 500mg Injection?

No Side Effec*

100%

*No Side Effect

Please rate Desferal 500mg Injection on price

Expensive

100%

Related lab tests

Iron Serum

Iron Studies

Total Iron Binding Capacity

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Byrns MC, Penning TM. Environmental Toxicology: Carcinogens and Heavy Metals. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1875-76.
Kosnett MJ. Heavy Metal Intoxication & Chelators. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1010.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 365-66.
Deferoxamine. Hurley, Maidenhead: Hospira UK Ltd.; 2001 [revised Aug. 2017]. [Accessed 6 Apr. 2019] (online) Available from:
Mayo Clinic. Deferoxamine. [Accessed 6 Apr. 2019] (online) Available from:
Drugs.com. Deferoxamine. [Accessed 21 Feb. 2019] (online) Available from:
Deferoxamine. Stein, Switzerland: Novartis Pharma Stein AG; 2011. [Accessed 6 Apr. 2019] (online) Available from:

Marketer details

Name: Novartis India Ltd

Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Country of origin: India

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Desferal 500mg Injection

Product introduction

Uses of Desferal Injection

Benefits of Desferal Injection

In Iron overload

Side effects of Desferal Injection

Common side effects of Desferal

How to use Desferal Injection

Safety advice

All substitutes

Quick tips

Fact Box

Patient concerns

User feedback

Want to share the information?

Disclaimer:

References

Marketer details

Lab tests offered by us