Comantrel-T Tablet is used alone or in combination with other medicines to treat Parkinson’s disease. It can also be used to treat drug-induced movement disorder. It works by increasing the levels of a chemical called dopamine in the brain, which is important for controlling movement.

Comantrel-T Tablet is used to treat Parkinson's disease (a disorder of the nervous system that causes difficulties with movement and balance) by improving muscle control and reducing stiffness.

Uses of Comantrel Tablet

Treatment of Parkinson's disease

Benefits of Comantrel Tablet

In Treatment of Parkinson's disease

Comantrel-T Tablet is one of the most effective medications to relieve symptoms of Parkinson's disease such as tremors, muscle stiffness and difficulty moving. It increases the amount of a chemical called dopamine in the brain which helps in coordination of body movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.

Side effects of Comantrel Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Comantrel

Nausea
Dryness in mouth
Constipation
Dizziness
Blurred vision
Insomnia (difficulty in sleeping)
Hallucination
Peripheral edema
Balance disorder (loss of balance)
Orthostatic hypotension (sudden lowering of blood pressure on standing)

How to use Comantrel Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Comantrel-T Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Comantrel Tablet works

Comantrel-T Tablet is a dopamine agonist that treats Parkinson's disease. It works by increasing the amount of dopamine, a chemical messenger in the brain which regulates body movements. It also has an antiviral property. It works against viruses to prevent their growth and multiplication. It also appears to restricts the viruses to release infectious chemicals (viral nucleic acid) to enter into the body. Thus, it prevents and treats influenza infection.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Comantrel-T Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Comantrel-T Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Comantrel-T Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Comantrel-T Tablet may cause side effects which could affect your ability to drive.

Kidney

CAUTION

Comantrel-T Tablet should be used with caution in patients with kidney disease. Dose adjustment of Comantrel-T Tablet may be needed. Please consult your doctor.
Use of Comantrel-T Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Comantrel-T Tablet should be used with caution in patients with liver disease. Dose adjustment of Comantrel-T Tablet may be needed. Please consult your doctor.
It may cause a transient increase in liver enzymes.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Comantrel-T Tablet

₹9.5/Tablet

Parkitidin Tablet

Sun Pharmaceutical Industries Ltd

₹12.4/tablet

31% costlier

Amantex Tablet

Intas Pharmaceuticals Ltd

₹13.13/tablet

38% costlier

Manotrel 100mg Tablet

Cmg Biotech Pvt Ltd

₹11.1/tablet

17% costlier

Ensorex 100mg Tablet

Alteus Biogenics Pvt Ltd

₹12.25/tablet

29% costlier

Amantrel Tablet

Cipla Ltd

₹13.47/tablet

42% costlier

Quick tips

It can be taken with or without food.
It may cause blurring of vision or affect mental ability. Do not drive or do anything requiring concentration until you know how it affects you.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Do not take extra medicine to make up for the missed dose.
It may put you at a higher risk of having seizures. Talk to your doctor if you have a history of seizures or are taking medication for it.
Inform your doctor if you notice an urge to gamble, increased sexual urges, binge eating, or uncontrolled spending.
Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class

Synthetic Tricyclic Amine Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Dopamine facilitator

Patient concerns

Parkinson's disease tremors ,Insomnia.

Dr. Ravi Shankar M.

Ayurveda

Use Dhanadanayanadi kashayam 15ml twice a day with 15 ml water before food and Zandopa 10 grams twice a day witk milk after food and Tab Dhanvantari Vati 1-0-1 after food for 2 months

Parkinson's disease for 25 yrs. Taking allopathy Suggestions needed

Dr. Deepak Kumar Soni

Ayurveda

Kindly consult to any good Ayuvedic Panchkarma center. Panchkarma therapy will give you some result .

My father has parkinson's disease from last 12 year. In last 2012 he got severe pneumonia and has been admitted in AIIMS .He was treated with various antibiotics.he came out but got bed ridden after that.From last few year he just sit on his own. he is currently taking bexol 1mg three times, syndopa 125 plus 3 times, ropark XL 3 times.now from few year he got hallucination and cound not sleep in night and constantly talking in night(Some Nights not always).During his stay in AIIMS Dr. prescribed quetiapine 12.5 mg which he is not currently taking.please advice some medicien so that he atleast can sleep at night.

Dr. Vikas Sharma

Neurology

Start Oleanz 2.5 mg at nite

FAQs

Does Comantrel-T Tablet cause constipation?

Yes, constipation is a common side effect of Comantrel-T Tablet, though it does not occur in everyone. Consult your doctor or a dietician if constipation persists and is troublesome.

Is Comantrel-T Tablet used for pain?

Though it is not an approved use, Comantrel-T Tablet has been shown to be effective in relieving pain related to nerve disorder. Comantrel-T Tablet is a prescription medicine, and you should take it for relief of pain only if advised by the doctor.

Does Comantrel-T Tablet cause fatigue?

Yes, Comantrel-T Tablet causes fatigue and sleepiness which may affect some patients’ ability to drive and operate machinery safely.

What happens when I stop taking Comantrel-T Tablet?

Do not stop taking this medicine or lower the dose without first checking with your doctor. If required, your doctor will gradually reduce the amount you take each day before stopping it completely. Abruptly stopping Comantrel-T Tablet may result in worsening of Parkinsonism. It may also cause delirium, agitation, delusions, hallucinations, paranoid reaction, stupor, anxiety, depression, or slurred speech.

Is Comantrel-T Tablet a dopamine agonist?

Yes, Comantrel-T Tablet is a dopamine agonist. Dopamine is needed to control movements in the brain. Comantrel-T Tablet works by increasing the amount of dopamine, thereby helping in controlling the movements in Parkinson’s disease.

Can I take Comantrel-T Tablet any time during the day? Should the dose be taken before meal?

Yes, Comantrel-T Tablet can be taken at any time during the day, with or without food. Try to take the medicine at about the same time each day, as directed by your doctor. Taking your medicine at the same time each day will have the best effect. It will also help you to remember when to take your medicine.

Can Comantrel-T Tablet get you high?

The use of Comantrel-T Tablet may cause impulse control disorders in which you may have strong urges to gamble, increased sexual urges, intense urges to spend money, binge eating, and other intense urges. Additionally, there is the inability to control these urges. If such symptoms are experienced then dose reduction or tapered discontinuation should be considered.

Does Comantrel-T Tablet affect fertility?

No, Comantrel-T Tablet is not known to affect fertility in humans.

Can Comantrel-T Tablet cause weight loss?

Decreased weight and body mass index may occur with continued Comantrel-T Tablet usage. If you have any concerns regarding weight loss consult your doctor or a nutritionist.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 477.
Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 619.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 48-49.
Amantadine. Bridgewater, New Jersey: Vertical Pharmaceuticals, LLC; 1966 [revised Feb. 2018]. [Accessed 19 Jun. 2019] (online) Available from:
Amantadine hydrochloride. Walsall, UK: Fontus Health Ltd.; 2019. [Accessed 19 Jun. 2019] (online) Available from:
Amantadine hydrochloride. North Ryde, New South Wales: NOVARTIS Pharmaceuticals Australia Pty Limited; 2014. [Accessed 19 Jun. 2019] (online) Available from:
ScienceDirect. Amantadine. [Accessed 19 Jun. 2019] (online) Available from:
Drugs.com. Amantadine Pregnancy and Breastfeeding Warnings. [Accessed 19 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Amantadine. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Amantadine Hydrochloride [Product Information]. Maple Grove, MN: Upsher-Smith Laboratories, LLC; 2022. [Accessed 09 Jun, 2023] (online) Available from:

Marketer details

Name: Consern Pharma Limited

Address: Consern Pharma Private Limited, Kuljive Mahajan(Mg. Director), Rural Focal Point, V.P.O. Tibba, Ludhiana - 141120, Punjab, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.