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Last updated
05 Dec 2023 | 06:14 PM (IST)

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Amantrel Tablet

Prescription Required
Marketer
SALT COMPOSITION
Storage
Store below 30°C
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Product introduction

Amantrel Tablet is used alone or in combination with other medicines to treat Parkinson’s disease. It can also be used to treat drug-induced movement disorder. It works by increasing the levels of a chemical called dopamine in the brain, which is important for controlling movement.

Amantrel Tablet is used to treat Parkinson's disease (a disorder of the nervous system that causes difficulties with movement and balance) by improving muscle control and reducing stiffness.

Uses of Amantrel Tablet

Benefits of Amantrel Tablet

In Treatment of Parkinson's disease

Amantrel Tablet is one of the most effective medications to relieve symptoms of Parkinson's disease such as tremors, muscle stiffness and difficulty moving. It increases the amount of a chemical called dopamine in the brain which helps in coordination of body movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.

Side effects of Amantrel Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amantrel

  • Nausea
  • Dryness in mouth
  • Constipation
  • Dizziness
  • Blurred vision
  • Insomnia (difficulty in sleeping)
  • Hallucination
  • Peripheral edema
  • Balance disorder (loss of balance)
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)

How to use Amantrel Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amantrel Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Amantrel Tablet works

Amantrel Tablet is a dopamine agonist that treats Parkinson's disease. It works by increasing the amount of dopamine, a chemical messenger in the brain which regulates body movements. It also has an antiviral property. It works against viruses to prevent their growth and multiplication. It also appears to restricts the viruses to release infectious chemicals (viral nucleic acid) to enter into the body. Thus, it prevents and treats influenza infection.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Amantrel Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Amantrel Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Amantrel Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Amantrel Tablet may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Amantrel Tablet should be used with caution in patients with kidney disease. Dose adjustment of Amantrel Tablet may be needed. Please consult your doctor.
Use of Amantrel Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Amantrel Tablet should be used with caution in patients with liver disease. Dose adjustment of Amantrel Tablet may be needed. Please consult your doctor.
It may cause a transient increase in liver enzymes.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Amantrel Tablet
₹13.47/Tablet
Parkitidin Tablet
Sun Pharmaceutical Industries Ltd
₹12.4/tablet
8% cheaper
Comantrel-T Tablet
Consern Pharma Limited
₹9.5/tablet
29% cheaper
Amantex Tablet
Intas Pharmaceuticals Ltd
₹13.13/tablet
3% cheaper
Manotrel 100mg Tablet
Cmg Biotech Pvt Ltd
₹11.1/tablet
18% cheaper
Ensorex 100mg Tablet
Alteus Biogenics Pvt Ltd
₹12.25/tablet
9% cheaper

Quick tips

  • It can be taken with or without food.
  • It may cause blurring of vision or affect mental ability. Do not drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Do not take extra medicine to make up for the missed dose.
  • It may put you at a higher risk of having seizures. Talk to your doctor if you have a history of seizures or are taking medication for it.
  • Inform your doctor if you notice an urge to gamble, increased sexual urges, binge eating, or uncontrolled spending.
  • Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class
Synthetic Tricyclic Amine Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Dopamine facilitator

Patient concerns

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Is there have any medicine 4 PD Hi sir ,good afternoon My father is suffering from Parkinson's disease since last 3years. Recently he is taking syndopa plus revemer 3,Ropark 25 and amantrel I am not getting any positive results
Dr. Deepak Kumar Soni
Ayurveda
https://www.1mg.com/otc/zandopa-powder-otc237392
Parkinson's disease tremors ,Insomnia.
Dr. Ravi Shankar M.
Ayurveda
Use Dhanadanayanadi kashayam 15ml twice a day with 15 ml water before food and Zandopa 10 grams twice a day witk milk after food and Tab Dhanvantari Vati 1-0-1 after food for 2 months
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User feedback


FAQs

Does Amantrel Tablet cause constipation?

Yes, constipation is a common side effect of Amantrel Tablet, though it does not occur in everyone. Consult your doctor or a dietician if constipation persists and is troublesome.

Is Amantrel Tablet used for pain?

Though it is not an approved use, Amantrel Tablet has been shown to be effective in relieving pain related to nerve disorder. Amantrel Tablet is a prescription medicine, and you should take it for relief of pain only if advised by the doctor.

Does Amantrel Tablet cause fatigue?

Yes, Amantrel Tablet causes fatigue and sleepiness which may affect some patients’ ability to drive and operate machinery safely.

What happens when I stop taking Amantrel Tablet?

Do not stop taking this medicine or lower the dose without first checking with your doctor. If required, your doctor will gradually reduce the amount you take each day before stopping it completely. Abruptly stopping Amantrel Tablet may result in worsening of Parkinsonism. It may also cause delirium, agitation, delusions, hallucinations, paranoid reaction, stupor, anxiety, depression, or slurred speech.

Is Amantrel Tablet a dopamine agonist?

Yes, Amantrel Tablet is a dopamine agonist. Dopamine is needed to control movements in the brain. Amantrel Tablet works by increasing the amount of dopamine, thereby helping in controlling the movements in Parkinson’s disease.

Can I take Amantrel Tablet any time during the day? Should the dose be taken before meal?

Yes, Amantrel Tablet can be taken at any time during the day, with or without food. Try to take the medicine at about the same time each day, as directed by your doctor. Taking your medicine at the same time each day will have the best effect. It will also help you to remember when to take your medicine.

Can Amantrel Tablet get you high?

The use of Amantrel Tablet may cause impulse control disorders in which you may have strong urges to gamble, increased sexual urges, intense urges to spend money, binge eating, and other intense urges. Additionally, there is the inability to control these urges. If such symptoms are experienced then dose reduction or tapered discontinuation should be considered.

Does Amantrel Tablet affect fertility?

No, Amantrel Tablet is not known to affect fertility in humans.

Can Amantrel Tablet cause weight loss?

Decreased weight and body mass index may occur with continued Amantrel Tablet usage. If you have any concerns regarding weight loss consult your doctor or a nutritionist.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 477.
  2. Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 619.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 48-49.
  4. Amantadine. Bridgewater, New Jersey: Vertical Pharmaceuticals, LLC; 1966 [revised Feb. 2018]. [Accessed 19 Jun. 2019] (online) Available from:External Link
  5. Amantadine hydrochloride. Walsall, UK: Fontus Health Ltd.; 2019. [Accessed 19 Jun. 2019] (online) Available from:External Link
  6. Amantadine hydrochloride. North Ryde, New South Wales: NOVARTIS Pharmaceuticals Australia Pty Limited; 2014. [Accessed 19 Jun. 2019] (online) Available from: External Link
  7. ScienceDirect. Amantadine. [Accessed 19 Jun. 2019] (online) Available from:External Link
  8. Drugs.com. Amantadine Pregnancy and Breastfeeding Warnings. [Accessed 19 Mar. 2019] (online) Available from:External Link
  9. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Amantadine. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:External Link
  10. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link
  11. Amantadine Hydrochloride [Product Information]. Maple Grove, MN: Upsher-Smith Laboratories, LLC; 2022. [Accessed 09 Jun, 2023] (online) Available from:External Link

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of origin: India

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