Addison's disease

Addison's disease is a rare disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the adrenal gland. Adrenal glands are located on top of your kidneys and produce many hormones for the normal functioning of the body.

Symptoms generally come on slowly and may include abdominal pain, muscle weakness, and weight loss. Darkening of the skin in certain areas may also be seen.

Addison's disease mostly affects middle-aged females. Risk factors include certain medications, sepsis, and bleeding into both adrenal glands.

Treatment involves replacing the absent hormones. The prescribed medications are usually taken lifelong, and regular follow-up treatment and monitoring for other health problems are also required.