Vitamin D (25 OH) + Vitamin B12 near me in Ghaziabad

Vitamin B12 is a part of B complex of vitamins. Vitamin B12 is also called as Cobalamin. It is a water soluble vitamin. Vitamin B12 plays an important role in formation of normal red blood cells, repair of tissues, DNA synthesis and genetic material in cells. It is not produced in the body and has to be taken in diet. The diet sources include red meat, fish, milk, poultry, yoghurt, eggs, fortified cereals, breads and other grain products. It can also be taken in the form of Vitamin B12 tablets or multivitamin pills. The deficiency of Vitamin B12 results in macrocytic anemia (size of red blood cells larger than normal).

Megaloblastic anemia is a type of macrocytic anemia, in which large size red blood cells called as macrocytes are produced. These red blood cells are fewer in number. There is a decrease in white blood cell count and platelet count. Megaloblastic anemia occurs due to acquired deficiency of Vitamin B12. The reason can be an inadequate dietary intake of Vitamin B12 or any problem in the absorption of Vitamin B12 from the intestines.

In case of problem in the absorption of Vitamin B12 from intestines, it is known as Pernicious anemia. It occurs due to lack of intrinsic factor which is present in secretions of the stomach.

Vitamin B12 is also important for nerve health and is taken as a nutritional supplement for the treatment of nerve damage.

Vitamin B12 binds with intrinsic factor (protein secreted by cells in the stomach). After binding, a complex is formed which is absorbed by the small intestine. In case of any disease interfering in this process can cause weakening of absorption of Vitamin B12.   

Vitamin D Test measures the levels of Vitamin D in the blood. Two forms of vitamin D can be measured in the blood, 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D. The 25-hydroxyvitamin D is the major form found in the blood and is the relatively inactive precursor to the active hormone, 1,25-dihydroxyvitamin D. Because of its long half-life and higher concentration, 25-hydroxyvitamin D is commonly measured to assess and monitor vitamin D status in individuals.

The 25-hydroxyvitamin D test is done to determine the level of Vitamin D in your blood, whether it is low or higher than normal. Low levels can be seen if a person is not getting enough exposure to sunlight or enough dietary vitamin D to meet his or her body's demand or if there is a problem with its absorption from the intestines (cystic fibrosis, crohn’s disease, who have undergone gastric bypass surgery). Sometimes, medicines used to treat seizure (Phenytoin) can cause Vitamin D deficiency by interfering with transformation to 25-hydroxyvitamin D in the liver. Severe liver and kidney diseases can also cause vitamin D deficiency. High levels reflects excess supplementation of the vitamin.