Triple Marker with Graph (2nd Trimester) near me in Dombivli

This test measures three markers which include AFP, HCG, and estriol in the blood. As there are three markers involved, it is known as the Triple Marker test.

AFP is a protein which is produced by the fetus. If the levels of AFP are high, it indicates neural tube defects in the fetus or there can be incomplete closure of the fetus abdomen.

HCG hormone is produced by cells of the placenta. If the levels of HCG are low, it indicates a miscarriage or ectopic pregnancy. Whereas, if the levels of HCG are high this indicates multiple pregnancies.

Estriol is a form of the hormone estrogen which is present in both fetus and placenta. If the levels of estriol are low, it indicates the risk of the baby getting delivered with Down syndrome especially when the levels of AFP are low and HCG are high.

If the levels of all these three markers are abnormal, there can be a presence of neural tube defects like spina bifida (spinal cord fails to develop properly), anencephaly (absence of brain, skull, and scalp), and multiple pregnancies (twins or triplets).

     This test is done between 15-20 weeks of pregnancy. Females who are 35 years or more, have a family history of birth defects, or have diabetes or are using insulin have a higher risk of getting abnormal values of these markers. Exposure to high levels of radiation or having the viral infection during pregnancy can also be considered as possible risk factors associated with these high levels. This test is also helpful to indicate any complications in the fetus after birth.