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Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
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Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Prolactin

(PRL)
312538 42% Off
This test is for
Male, Female
Test Preparation
  1. Overnight fasting is preferred.

Understanding Prolactin


What is Prolactin?

Prolactin test measures the level of prolactin, a hormone produced by the pituitary gland, in the blood. The hormone plays a key role in breast growth and milk production during pregnancy and after childbirth.

Prolactin levels are normally high for pregnant women and new mothers. Higher levels of prolactin in non-pregnant women and men are indicative of prolactinoma (tumor of the pituitary gland), liver disease, and hypothyroidism whereas low levels may indicate hypopituitarism. Some birth control pills, high blood pressure drugs, or antidepressants can affect the test results.

What is Prolactin used for?


  • To investigate the cause of abnormal breast milk discharge (galactorrhea), menstrual irregularities or infertility in non-pregnant women

  • To evaluate the role of prolactin in case of lactation failure in women after childbirth

  • To investigate the cause of erection problems, testicular failure or abnormal breast discharge in men

  • To investigate the cause of loss of sex drive (libido) in both men and women

  • To detect and monitor the progress of prolactinoma (tumor of the pituitary gland that causes high levels of prolactin) in both men and women

Interpreting Prolactin results


Interpretations

High levels of prolactin can be seen in:

  • Tumors of the pituitary gland that produces and releases prolactin (Prolactinoma)

  • Diseases of the hypothalamus (a gland located in the brain)

  • Kidney disease

  • Liver disease

  • Hypothyroidism

  • Polycystic ovary disease (PCOD)

  • Conditions like anorexia nervosa (eating disorder)

Low levels of prolactin can be seen in:

  • Pseudohypoparathyroidism

  • Patients taking bromocriptine

  • Pituitary deficiency like necrosis or infarction of the pituitary gland

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Prolactin


Frequently Asked Questions about Prolactin

Q. Which medicines can affect the levels of Prolactin hormone?

Certain drugs can cause a low level of Prolactin such as Dopamine (used in conditions like shock), Levodopa (used for Parkinson’s disease), or Ergot alkaloid derivatives (used for severe headaches). However, certain drugs can cause elevated levels of Prolactin such as CNS depressants, Estrogen, drugs used for the treatment of hypertension (e.g., Reserpine, Verapamil, Methyldopa), and drugs used for treating gastroesophageal reflux like cimetidine.

Q. Are there any other conditions which can alter the levels of Prolactin?

Yes, there are other conditions in which high levels of prolactin can be seen, for eg., lung cancer, seizures, trauma to the chest wall, stress due to illness and use of Marijuana.

Q. The test results showed high prolactin levels. Do I require any other tests?

When the prolactin levels are high, the doctor may advise you to get Follicle stimulating hormone (FSH) test, Luteinizing hormone (LH) levels to assess fertility problems. The testosterone test is advised in males when the prolactin level is found high. The doctor may also advise for MRI scan for the diagnosis of prolactinoma.

Q. I got my Prolactin levels tested. Now, my doctor has advised me thyroid test. Why is it so?

In many patients, high levels of Prolactin are seen along with low levels of thyroid hormones (hypothyroidism), so you may be asked to get your thyroid tests done. However, high levels of Prolactin does not cause low levels of thyroid hormones.

Q. What is prolactinoma?

Prolactinomas are tumors which are usually benign (non-cancerous) of the pituitary gland in which there is production of high amounts of prolactin. These are more common in women as compared to men. Prolactinomas may cause menstrual irregularities, infertility, and bone loss in women. However, in men it can cause erectile dysfunction, gynecomastia (breast enlargement), decreased muscle mass, and bone loss. If the size of the tumor is quite large, it can cause pressure symptoms like headache and problems of the vision.

Q. Are there any foods which can decrease the levels of prolactin?

Yes, foods rich in vitamin B6 like bananas, potatoes, chicken or spinach, foods rich in zinc (e.g., beef, turkey, beans, shellfish) and zinc supplements can decrease the prolactin levels.

Q. Are there any foods which can increase the levels of prolactin?

Yes, foods such as barley (jau), fennel (saunf) and fenugreek (methi) seeds, oats, whole wheat, brown rice, and papaya can increase the levels of prolactin. These foods are considered to be helpful in milk production in new mothers.

Q. Is there any risk associated with this test?

There is no risk associated with the test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.
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Prolactin test price for other cities


Price inAhmedabadRs. 312
Price inAllahabadRs. 414
Price inBangaloreRs. 414
Price inBhopalRs. 414
Price inChandigarhRs. 414
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