Human Leukocyte Antigen B27 near me in Chennai

Also referred as

HLA B27 PCR

For men & women

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HLA B-27, also called Human leukocyte antigen B-27, is a blood test indicated to look for a protein (HLA B-27), present on the surface of white blood cells. Presence of HLA B-27 may indicate a possibility of autoimmune disease, where the guarding cells (WBC) attacks own cells.

This test is done if one experiences symptoms of arthritis such as chronic joint pain, stiffness, and inflammation in the lower back. It may also be advised in case of inflammation of the eyes, especially in males.

People with HLA B-27 have increased chances of developing autoimmune diseases like rheumatoid arthritis and reactive arthritis. B-27 is also said to be linked with inflammatory bowel disease and other chronic conditions.

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What does Human Leukocyte Antigen B27 measure?

HLA B-27 test determines the presence or absence of human leukocyte antigen which is present on the surface of white blood cells. The HLA B-27 also refers to the gene which codes for the HLA B-27 protein.

HLA B-27 are proteins that help the immune system to differentiate the body’s own cells from other foreign cells. Every person has an inherited combination of HLA genes which codes for many antigens that are present on the surfaces of their cells. This HLA combination is distinctive for each person and is based on the presence or absence of each antigen.

People with HLA B-27 have increased chances of developing autoimmune diseases like ankylosing spondylitis, rheumatoid arthritis, reactive arthritis, and isolated acute anterior uveitis. HLA B-27 is also said to be linked with inflammatory bowel disease and other chronic conditions.

Content created by

Dr. Swati Gupta (Anand)

MBBS, MD Lab Medicine

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Last Updated

25th Oct 2023