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Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
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Anti Aquaporin 4 / NMO Ab

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Male, Female

Understanding Anti Aquaporin 4 / NMO Ab


What is Anti Aquaporin 4 / NMO Ab?

Anti aquaporin 4/NMO Ab is a quantitative test used to detect the presence of antibody aquaporin 4 in patients suffering from neuromyelitis optica and also to characterize reasons for anti AQP4 antibodies. Aquaporin 4 is the major antigen present in neuromyelitis optica and its antibodies can easily be detected using the anti aquaporin 4 or NMO Ab test.


Neuromyelitis optica (NMO) is a rare autoimmune disease that destroys the myelin sheath of the optic nerve as well as the spinal cord, thereby resulting in NMO aquaporin. In NMO aquaporin, a patient has temporary or permanent loss of vision in one or both eyes. As of now, there is no cure for NMO.

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