Thalep 400mg Tablet is a medicine used in the treatment of chronic iron overload caused by frequent blood transfusion. It helps remove the excess iron from the body and reduce the risk of it causing organ damage.

Repeated blood transfusions in some patients can cause a build-up of excess iron. Thalep 400mg Tablet is used to remove the excess iron from the body

Uses of Thalep Tablet

Treatment of Iron overload

Benefits of Thalep Tablet

In Treatment of Iron overload

Iron overload, as the name suggests, means excess of iron in the human body. Too much iron can cause organ damage, which can lead to conditions such as cancer, irregular heartbeat and cirrhosis of the liver. Symptoms are related to conditions that arise from iron overload such as high blood sugar levels (diabetes), darkening of the skin, abnormal heart rhythm or arthritis. By using Thalep 400mg Tablet, this excess of iron can be decreased to safe levels by removing it from the body through stools. This helps to reduce the risk of organ damage and prevents further complications. Take Thalep 400mg Tablet as prescribed by the doctor to get the maximum benefit.

Side effects of Thalep Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Thalep

Nausea
Headache
Vomiting
Rash
Abdominal pain
Constipation
Itching
Increased liver enzymes
Abdominal distension
Diarrhea

How to use Thalep Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Thalep 400mg Tablet is to be taken empty stomach.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Thalep 400mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Thalep 400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Thalep 400mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Thalep 400mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

UNSAFE

Thalep 400mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.

Liver

CAUTION

Thalep 400mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Thalep 400mg Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Thalep 400mg Tablet in these patients.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Thalep 400mg Tablet

₹32.5/Tablet

Desifer 400 Tablet

Natco Pharma Ltd

₹90/tablet

177% costlier

Quick tips

Thalep 400mg Tablet is used to reduce excess iron from the body.
Inform your doctor if you also have upper stomach pain, clay-colored stools, or jaundice (yellowing of your skin or the whites of your eyes).
Take an adequate amount of water while taking Thalep 400mg Tablet.
Thalep 400mg Tablet may cause dizziness. It is advisable not to drive or operate any machinery until you feel normal again.
If you are taking any antacid, take them 2 hours before or after Thalep 400mg Tablet.
Inform your doctor if you have any liver or kidney disease.
Inform your doctor if you are pregnant or breastfeeding.

Fact Box

Chemical Class

Triazole & benzoate derivative

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Iron chelating agents

Patient concerns

Hello doctor I have thallassemia major since birth and due to iron overload of repetitive blood transfusion i have diagnosed with diabetes 3 yr ago -at the time of diabetes diagnosis my sugar level is 650 mg/dl. Now according to my case what could be the state of my diabetes type 1 or type 2 ?

Dr. Amit Modi

Paediatrics

Hello, Diabetes in thalassaemia is thought to be caused mainly by iron overload, from repeated blood transfusions, damaging the pancreas. Insulin secretion may be reduced, possibly because iron is directly toxic to the insulin producing pancreatic ?-cells. So it is type 1 DM .

Hello doctor i have thallasemia major since birth and due to iron overload of repetitive blood transfusions from this disease i was diagnosed with diabetes 2 yrs. ago Now my query is can i control my sugar by controlling iron/ferritin?

Dr. Ashwin Porwal

Internal Medicine

No you have to take insulin or Oral hypoglycemic agents for it

Respected mam/sir, Am recently married and I have been suffered from mensus problem and I take treatmnt in homeocare international.Now my problem was cleared.But my hb range is 8.9.Is this range is enough for pregnancy?S baby formation is possible for me?How to increase my hb range? Kindly request you to clear my doubts.Thank you.

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Take iron tablets and iron rich diet

FAQs

What is Thalep 400mg Tablet used for?

Thalep 400mg Tablet is used for removing excess iron from the body due to repeated blood transfusions in patients with beta thalassemia major (a blood disorder)

How does Thalep 400mg Tablet work?

Thalep 400mg Tablet works by binding to excess iron in the blood and removing it from the body through stool.

Related lab tests

Iron Serum

Iron Studies

Total Iron Binding Capacity

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

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Kosnett MJ. Heavy Metal Intoxication & Chelators. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1010.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 365.
Deferasirox. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2006 [revised 23 Jul. 2018]. [Accessed 6 Apr. 2019] (online) Available from:
Medscaape. Deferasirox. [Accessed 6 Apr. 2019] (online) Available from:
Deferasirox. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2006 [revised 23 Jul. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
Drugs.com. Deferasirox Pregnancy and Breastfeeding Warnings. [Accessed 6 Apr. 2019] (online) Available from:
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Marketer details

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Country of origin: India

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