Spnib 50 Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.

Spnib 50 Tablet is used to treat different types of cancer

Uses of Spnib Tablet

Blood cancer (Chronic myeloid leukaemia)

Benefits of Spnib Tablet

In Blood cancer (Chronic myeloid leukaemia)

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Spnib 50 Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Spnib Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Spnib

Abdominal pain
Anemia (low number of red blood cells)
Breathing problems
Fatigue
Fever
Headache
Infection
Low blood platelets
Musculoskeletal (bone, muscle or joint) pain
Nausea
Rash
Vomiting

How to use Spnib Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Spnib 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Spnib 50 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Spnib 50 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Spnib 50 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Spnib 50 Tablet may cause side effects which could affect your ability to drive.
Take special care when driving in case you experience side effects such as dizziness and blurred vision with Spnib 50 Tablet.

Kidney

SAFE IF PRESCRIBED

Spnib 50 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Spnib 50 Tablet may not be needed in these patients. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Spnib 50 Tablet is safe to use in patients with liver disease. No dose adjustment of Spnib 50 Tablet is recommended.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Spnib 50 Tablet

₹51.58/Tablet

Sprycel 50mg Tablet

BMS India Pvt Ltd

₹3287.3/tablet

6273% costlier

Dasaloid 50mg Tablet

Neon Laboratories Ltd

₹51.58/tablet

same price

Dasamac 50 Tablet

Admac Pharma Ltd

₹129.03/tablet

150% costlier

Leu Kinib 50mg Tablet

Sayre Therapeutics Pvt Ltd

₹20.25/tablet

61% cheaper

Dasamed 50mg Tablet

Medicamen Biotech Ltd

₹90/tablet

74% costlier

View all substitutes

Quick tips

Take it with or without food, preferably at the same time each day.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Fact Box

Chemical Class

Pyrimidine and Thiazole Derivetive

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine kinase inhibitors

Patient concerns

She is suffering from chronic myeloid leukemia

Dr. Deepak Kumar Soni

Ayurveda

Hi Kindly consult to Ayurvedic doctor at your local city area , face to face consult is needed.

Mh mother have blood cancer .recently she got her first induction chemotherapy.in CBC test Immature myeloid cells 18 percent what are indicate.is it serious .is it shown presence of cancer in blood old tell me

Dr. Ila Jain Khandelwal

Pathology

Dear Mam Greetings from 1mg, The reports shows low hemoglobin and platelet count which can be due to chemotherapy.

I want to know the symptoms of cancer as I am a smoker

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.

Related lab tests

Bcr-Abl Gene Translocation (Qualitative)

Bcr-Abl Gene Translocation (Quantitative)

Complete Blood Count

Peripheral Smear Examination

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1732-34.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 953.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 361-62.
Dasatinib monohydrate. Dublin, Ireland: Bristol-Myers Squibb Pharma; 2006 [revised 06 Feb. 2019]. [Accessed 26 Mar. 2019] (online) Available from:
Drugs.com. Dasatinib Pregnancy and Breastfeeding Warnings. [Accessed 26 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dasatinib. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Marketer details

Name: Zydus Cadila

Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.