Pirfenex 400mg Tablet
Prescription Required
Product introduction
Pirfenex 400mg Tablet is a prescription medicine used in the treatment of idiopathic pulmonary fibrosis. It reduces scarring and swelling in the lungs and helps to breathe better.
Pirfenex 400mg Tablet is used for treating mild to moderate disease of lungs that have become swollen and scarred (marks left on surface due to wound) overtime that makes breathing difficult
Pirfenex 400mg Tablet is used for treating mild to moderate disease of lungs that have become swollen and scarred (marks left on surface due to wound) overtime that makes breathing difficult
Uses of Pirfenex Tablet
Benefits of Pirfenex Tablet
In Treatment of Idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis is a lung disease caused by lung tissue becoming thick and stiff and eventually forming scar tissue within the lungs. The scarring, or fibrosis, seems to result from a cycle of damage and healing that occurs in the lungs. These changes are irreversible and the affected person may experience shortness of breath or dry cough as initial symptoms. Pirfenex 400mg Tablet reduces the scarring or fibrosis and makes breathing easier. You may experience some bothersome side effects. Discuss with your doctor if you have any doubts.
Side effects of Pirfenex Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pirfenex
- Insomnia (difficulty in sleeping)
- Headache
- Dizziness
- Tiredness
- Sinus inflammation
- Loss of appetite
- Upper respiratory tract infection
- Weight loss
- Nausea
- Indigestion
- Diarrhea
- Photosensitivity
How to use Pirfenex Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pirfenex 400mg Tablet is to be taken with food.
How Pirfenex Tablet works
Pirfenex 400mg Tablet is an antifibrotic medication. It works by blocking the action of a certain natural substance in the body that is involved in causing fibrosis. This reduces the scarring and swelling in the lungs and makes breathing easier.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pirfenex 400mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pirfenex 400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Pirfenex 400mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Pirfenex 400mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Pirfenex 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pirfenex 400mg Tablet may be needed. Please consult your doctor.
Use of Pirfenex 400mg Tablet is not recommended with severe kidney disease and dialysis patients.
Use of Pirfenex 400mg Tablet is not recommended with severe kidney disease and dialysis patients.
Liver
CAUTION
Pirfenex 400mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Pirfenex 400mg Tablet may be needed. Please consult your doctor.
Use of Pirfenex 400mg Tablet is not recommended in patients with severe liver disease.
Use of Pirfenex 400mg Tablet is not recommended in patients with severe liver disease.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Pirfenex 400mg Tablet reduces scarring and swelling in the lungs, and helps you breathe better.
- It is best to take this medicine with food and at the same time each day.
- This medication may make you more sensitive to sun. Use sunscreen and wear protective clothing when outdoors.
- Stop smoking during treatment with Pirfenex 400mg Tablet as it can reduce the effect of the treatment.
- It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- It may cause weight loss. Monitor your weight regularly.
- Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin (jaundice).
Fact Box
Chemical Class
Pyridones Derivative
Habit Forming
No
Therapeutic Class
RESPIRATORY
Action Class
Idiopathic pulmonary fibrosis (IPF)
Patient concerns
FAQs
What monitoring will I need during treatment with Pirfenex 400mg Tablet?
Your doctor will check your liver function before starting treatment with Pirfenex 400mg Tablet. This test will be repeated monthly for the first 6 months and then it will be done after every three months. In addition to that, your doctor will also monitor your lung function periodically in order to see the response to Pirfenex 400mg Tablet.
Why is it important to continue treatment with Pirfenex 400mg Tablet?
It is important to control the progression of the disease by preserving your lung function which cannot be restored, once lost. Hence, it is highly recommended to start and continue the treatment with Pirfenex 400mg Tablet as prescribed by your doctor. Doing so can help preserve the existing lung function.
What are the side effects of Pirfenex 400mg Tablet?
Most common side effects of Pirfenex 400mg Tablet include skin sensitivity to sunlight, nausea, tiredness, diarrhea, indigestion or upset stomach, loss of appetite, and headache. Other common side effects include infections of the throat or the airways, bladder infections, weight loss, difficulty sleeping, dizziness, sleepiness, changes in taste, hot flushes, shortness of breath, and cough. Additionally, one may experience stomach problems such as acid reflux, vomiting, bloating, abdominal pain and discomfort, heart burn, constipation, skin problems such as itchy skin, skin redness or red skin, dry skin, skin rash, muscle pain, aching joints/joint pains, weakness, chest pain, and sunburn. It is possible that after using Pirfenex 400mg Tablet blood tests may show increased levels of liver enzymes.
Is Pirfenex 400mg Tablet a steroid?
No, Pirfenex 400mg Tablet is not a steroid. It belongs to pyridines group of medicines. It is used to treat idiopathic pulmonary fibrosis (IPF) in adults. In IPF, the tissues of the lungs get scarred and swell with time, which creates problem in breathing. This medicine helps reduce these effects to make you breathe better.
How do I know that Pirfenex 400mg Tablet is right for me?
Only you and your doctor can decide if Pirfenex 400mg Tablet is right for you. The doctor will only prescribe Pirfenex 400mg Tablet after assessing your condition. Based on your response to treatment and tolerability, you should continue the medicine.
If my disease is stable can I stop Pirfenex 400mg Tablet?
Idiopathic pulmonary fibrosis is a progressive disease though its progression is unpredictable. Do not stop the medication without consulting the doctor. Continue taking Pirfenex 400mg Tablet to slow down the progression of the disease.
What should I avoid while taking Pirfenex 400mg Tablet?
You should restrict sun exposure, while taking Pirfenex 400mg Tablet. Wear sunblock daily and cover your arms, legs, and head to reduce exposure to sunlight. Along with that, avoid smoking as it decreases the effect of Pirfenex 400mg Tablet.
What is the survival rate of pulmonary fibrosis?
The median survival of patients with pulmonary fibrosis is 2-3 years, yet some people live much longer. The factors which can be held responsible for shortened survival are older age, smoking history, and lower body mass index. The other factors can be more severe extent of disease both radiologically and physical impairment, and the development of other lung complications or conditions.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Medscape. Pirfenidone. [Accessed 01 Apr. 2019] (online) Available from:
- Pirefenidone. Brisbane, California: InterMune, Inc.; 2014. [Accessed 01 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
- CiplaMed. Pirfenidone [Prescribing Information]. [Accessed 05 Aug. 2023] (online) Available from:
Marketer details
Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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