Nitnib 50 Capsule is used in the treatment of kidney cancer and gastrointestinal stromal tumor.

Nitnib 50 Capsule is used to treat different types of cancer

Uses of Nitnib Capsule

Benefits of Nitnib Capsule

In Kidney cancer

Nitnib 50 Capsule is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.

In Gastrointestinal stromal tumour

A gastrointestinal stromal tumor (GIST) is a type of tumor that occurs most commonly in the stomach or small intestine. The tumors develop into the specialized cells called interstitial cells of Cajal (ICCs). Nitnib 50 Capsule helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit.

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Side effects of Nitnib Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nitnib

Nausea
Vomiting
Weakness
Rash
Abdominal pain
Indigestion
Discoloration of skin
Fatigue
Fever
Dry skin
High blood pressure
Diarrhea
Constipation
Painful blisters on hands and feet
Stomatitis (Inflammation of the mouth)
Hair discoloration
Pain in extremities
Back pain
Headache
Joint pain
Weight loss
Cough
Taste change
Breathlessness

How to use Nitnib Capsule

Take this medicine in the dose and duration as advised by your doctor. Nitnib 50 Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Nitnib Capsule works

Nitnib 50 Capsule is an anti-cancer medication. It works by binding and blocking certain cell surface protein (tyrosine kinase) responsible for the propagation of cancer growth. It also restricts the growth of new blood vessels within the tumor. This is how it prevents the proliferation of malignant cancers.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Nitnib 50 Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Nitnib 50 Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Nitnib 50 Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Nitnib 50 Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Nitnib 50 Capsule is safe to use in patients with kidney disease. No dose adjustment of Nitnib 50 Capsule is recommended.

Liver

CAUTION

Nitnib 50 Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Nitnib 50 Capsule may be needed. Please consult your doctor.
Limited information is available on the use of Nitnib 50 Capsule in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nitnib 50 Capsule

₹256.43/Capsule

Sunitibenz 50 Capsule

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₹268.93/capsule

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Sutent 50mg Capsule

Pfizer Ltd

₹8714.78/capsule

3299% costlier

Mitant 50mg Capsule

Hetero Healthcare Limited

₹260/capsule

1% costlier

Rcnet 50mg Capsule

BDR Pharmaceuticals Internationals Pvt

₹4.25/capsule

98% cheaper

Sunishil Capsule

Shilpa Medicare Ltd

₹25/capsule

90% cheaper

View all substitutes

Quick tips

Nitnib 50 Capsule is used for the treatment of thyroid cancer.
Take it with or without food, preferably at the same time each day.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
It may affect wound healing time. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
Monitoring of thyroid gland function is required while taking this medicine. Inform your doctor if you notice symptoms of weight gain, dry skin, and hair.
It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Inform your doctor about the consumption of Nitnib 50 Capsule before going for surgical procedure.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Fact Box

Chemical Class

Indole and Pyrrole Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine kinase inhibitors

Patient concerns

From last two months i found a pimple type on inner side of my lower lil. There is no pain in i Is there any risk of cancer

Dr. Vijay Sharnangat

Medical Oncology and Hematology

No risk for tumour

Right lung tumour cancer in upper portion In jalgaon district which oncologist is best for lung cancer.

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Dr Nitin Chaudhari us best oncologist

She is admitted in hospital for last 2 wks due to Plural effusion,ascites & Distended illium & jejunum portion,she has tested with USG of abdomen,Beta HCG, and tumor marker test,but In case of tumor marker test CA 125 is extensively high,its 945 dr. refers for a gynaecologist,what to do now ?? Dr. also aware to the patient,that they can operate Utectomy or may be cutting down of ovary is there any chance of CANCER ?

Dr. Megha Gupta

Obstetrics and Gynaecology

CA125 high indicates a ovarian tumour, which may or mayn't be malignant. For that surgery followed by tissue histopath reports will help in absolute diagnosis. The intestinal and effusion and acitis is not due to the ovarian tumour.

FAQs

How should I take Nitnib 50 Capsule?

You should take Nitnib 50 Capsule exactly as directed by your doctor. It should be started by doctors who have experience in administering cancer medicines. Take it once a day with or without food. Do not drink grapefruit juice or eat grapefruit during your treatment with Nitnib 50 Capsule, as the chances of side effects may be more.

Does Nitnib 50 Capsule have any effect on skin and hair?

During treatment with Nitnib 50 Capsule, your skin may get lighter and there may be hair loss. Also, patient may experience dryness, thickness or cracking of the skin, blisters, or rashes on the palms and soles. But, these side effects are reversible and go away once the medicine is stopped. Nitnib 50 Capsule may also cause serious skin reactions such as severe rash or rapidly spreading skin ulceration which could be fatal. Therefore, inform your doctor immediately if symptoms of infection occur around a skin injury. Let your doctor know if you have fever, pain, redness, swelling, or drainage of pus or blood.

What is the most important thing I need to know about Nitnib 50 Capsule?

Nitnib 50 Capsule can cause serious side effects such as severe liver problems that can lead to death. Therefore, tell your doctor right away if you experience itching, yellow eyes or skin, dark urine or pain or discomfort in the right upper stomach area. Your doctor will get blood tests done to check your liver function before and during treatment with Nitnib 50 Capsule. In case you develop liver problems, your doctor may stop the medicine temporarily or permanently.

Are generics available for Nitnib 50 Capsule? How does Nitnib 50 Capsule work?

There are no generics available for Nitnib 50 Capsule. Nitnib 50 Capsule blocks an enzyme which promotes the growth and spread of cancer cells. This enzyme is called protein kinase and is present on the surface of cancer cells. Blocking this enzyme stops the spread of cancer. Examples of other protein kinase inhibitors are erlotinib, gefitinib, lapatinib, vemurafenib and dasatinib.

Can Nitnib 50 Capsule be used in combination with other chemotherapy medicines?

There are no studies that support the use of Nitnib 50 Capsule with other chemotherapy medicines. For example, Nitnib 50 Capsule is used in Gastrointestinal stromal tumour (GIST), a type of cancer of the stomach and bowel, when imatinib (another anticancer medicine) no longer works or the patient cannot take imatinib.

Does Nitnib 50 Capsule have any effect on blood sugar levels in diabetics?

Yes, Nitnib 50 Capsule may decrease your blood sugar levels. Therefore, if you are a diabetic, you need to be extra careful since your blood sugar levels may become so low that you may become unconscious. Keep a regular check on the blood sugar levels, based on which your dose of anti-diabetics may be changed.

Can Nitnib 50 Capsule cause any change in blood pressure?

Generally, Nitnib 50 Capsule is known to cause an increase in blood pressure. Therefore, it is important that you keep a regular check on your blood pressure levels. Inform your doctor if you have severe headache, dizziness, lightheadedness or change in vision. Your doctor may prescribe a medicine to treat the increase blood pressure or may stop your treatment temporarily till your blood pressure returns to normal.

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Related lab tests

Complete Blood Count

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1740.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 955.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1304.
Sunitinib malate. New York, New York: Pfizer Inc.; 2006 [revised May 2011]. [Accessed 24 Jan. 2019] (online) Available from:
Drugs.com. Sunitinib Pregnancy and Breastfeeding Warnings. [Accessed 27 Mar. 2019] (online) Available from:
Sunitinib malate. Sandwich, Kent: Pfizer Limited; 2006 [revised Feb. 2019]. [Accessed 27 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Marketer details

Name: Zydus Cadila

Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.