Nindanib 100 Soft Gelatin Capsule is used in the treatment of idiopathic pulmonary fibrosis and non-small cell lung cancer. It works by targeting certain pathways involved in the growth and progression of these diseases and helps to stop or slow the spread of cancer cells.

Nindanib 100 Soft Gelatin Capsule is used to treat different types of cancer

Uses of Nindanib Soft Gelatin Capsule

Benefits of Nindanib Soft Gelatin Capsule

In Treatment of Idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis is a lung disease caused by lung tissue becoming thick and stiff and eventually forming scar tissue within the lungs. The scarring, or fibrosis, seems to result from a cycle of damage and healing that occurs in the lungs. These changes are irreversible and the affected person may experience shortness of breath or dry cough as initial symptoms. Nindanib 100 Soft Gelatin Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. You may experience some bothersome side effects. Discuss with your doctor if you have any doubts.

In Treatment of Non-small cell lung cancer

Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Nindanib 100 Soft Gelatin Capsule helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

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Side effects of Nindanib Soft Gelatin Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nindanib

Diarrhea
Nausea
Abdominal pain
Vomiting
Abnormal liver function tests
Loss of appetite
Headache
Weight loss
High blood pressure

How to use Nindanib Soft Gelatin Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nindanib 100 Soft Gelatin Capsule is to be taken with food.

How Nindanib Soft Gelatin Capsule works

Nindanib 100 Soft Gelatin Capsule is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. It also blocks pathways in the body that result in fibrosis, which is the thickening or scarring of the tissue. This helps to stop or slow the spread of cancer cells.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Nindanib 100 Soft Gelatin Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Nindanib 100 Soft Gelatin Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Nindanib 100 Soft Gelatin Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Nindanib 100 Soft Gelatin Capsule may cause side effects which could affect your ability to drive.
You may feel sick after taking this medicine and this could affect your driving.

Kidney

CAUTION

Nindanib 100 Soft Gelatin Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Nindanib 100 Soft Gelatin Capsule may be needed. Please consult your doctor.
There is limited information available on the use of Nindanib 100 Soft Gelatin Capsule in these patients.

Liver

CAUTION

Nindanib 100 Soft Gelatin Capsule should be used with caution in patients with liver disease. Dose adjustment of Nindanib 100 Soft Gelatin Capsule may be needed. Please consult your doctor.
Use of Nindanib 100 Soft Gelatin Capsule is not recommended in patients with moderate to severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nindanib 100 Soft Gelatin Capsule

₹66.0/Soft Gelatin Capsule

Cyendiv 100mg Soft Gelatin Capsule

Boehringer Ingelheim

₹1299.25/soft gelatin capsule

1869% costlier

Fibnib 100mg Soft Gelatin Capsule

Alkem Laboratories Ltd

₹82.5/soft gelatin capsule

25% costlier

Nindev 100mg Soft Gelatin Capsule

Zydus Cadila

₹79.5/soft gelatin capsule

20% costlier

Nintena 100mg Soft Gelatin Capsule

Sun Pharmaceutical Industries Ltd

₹71.3/soft gelatin capsule

8% costlier

Idofnib 100 Soft Gelatin Capsule

Lupin Ltd

₹75/soft gelatin capsule

14% costlier

Fact Box

Chemical Class

Indolecarboxylic Acids

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine kinase inhibitors

Patient concerns

Can idiopathic pulmonary fibrosis be cured?

Dr. Manju Singh

Homeopathy

I would like to suggest you that please consult with your nearest homeopathy doctor because your case require detail case taking.

What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma

Dr. Vijay Sharnangat

Medical Oncology and Hematology

This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.

My mother is suffering from Interstitial Lungs disease since 4 yrs.She is on home oxygen since 3 yrs from then for atleast 14-16 hrs.Currently she is getting treatment from AIIMS,New Delhi and the medecines given are as under:- Pirfenidone (600mg-Thrice a day) Sildenafil (25mg-Thrice a day) Tab Uprise D3 for calcium-60000 units (Once a month) Tab DDR60-Once a day. The treatment has been for exactly 1 yrs and 3 months from now but the disease is still on a progressive mode.She is not improving.My family is very worried. Please help out with proper treatment for this disease.This disease is also known as Idiopathic Pulmonary Fibrosis (IPF). Best Regards Mayur PATIENT

Dr. Aanchal Maheshwari

Ayurveda

Case has to be correlated with Ayurveda, for this case has to be seen in person before starting the treatment as correlation of case with Ayurveda need to be done

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References

Nintedanib. Ridgefield, Connecticut: Boehringer Ingelheim Pharmaceuticals, Inc.; 2014. [Accessed 26 Mar. 2019] (online) Available from:
Nintedanib esilate. Bracknell, Berkshire: Boehringer Ingelheim Limited; 2015 [revised 31 Oct. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Nintedanib. [Accessed 26 Mar. 2019] (online) Available from:
CiplaMed. Nintedanib [Prescribing Information]. [last Revised: 19 Mar. 2021]. [Accessed 02 Aug. 2023] (online) Available from:

Marketer details

Name: Glenmark Pharmaceuticals Ltd

Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.