Letrafem 2.5 Tablet helps treat breast cancer in post-menopausal women. It may be used alone or with other treatments, such as surgery or radiation. It can also be used in patients with advanced breast cancer to stop the tumor from spreading to other parts of the body.

Letrafem 2.5 Tablet is used to treat breast cancer in women who have gone through the menopause.

Uses of Letrafem Tablet

Treatment of Breast cancer
Treatment of Infertility due to anovulation

Benefits of Letrafem Tablet

In Treatment of Breast cancer

Letrafem 2.5 Tablet relieves the symptoms of breast cancer such as breast lumps, bloody discharge from the nipple, or changes in the shape or texture of the breast. It works by altering the production of those hormones in the body that are essential for the growth and spread of breast cancer. It may also interact with other hormones or have a direct effect on cancer to stop its growth.

In Treatment of Infertility due to anovulation

Letrafem 2.5 Tablet helps in the normal development of an egg in a woman's ovary (female reproductive organ) and stimulates the release of the egg during a process called ovulation. This helps to treat infertility in women. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective.

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Side effects of Letrafem Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Letrafem

Fatigue
Hypercholesterolemia (high cholesterol)
Increased sweating
Hot flashes
Bone pain
Dizziness
Joint pain
Edema (swelling)
Flushing (sense of warmth in the face, ears, neck and trunk)

How to use Letrafem Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Letrafem 2.5 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol

SAFE

Consuming alcohol with Letrafem 2.5 Tablet does not cause any harmful side effects.

Pregnancy

UNSAFE

Letrafem 2.5 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

UNSAFE

Letrafem 2.5 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Letrafem 2.5 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Letrafem 2.5 Tablet is safe to use in patients with kidney disease. No dose adjustment of Letrafem 2.5 Tablet is recommended.
However, there is limited information on the use of this medicine in patients with end stage kidney disease. Please consult with your doctor.

Liver

CAUTION

Letrafem 2.5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Letrafem 2.5 Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Letrafem 2.5 Tablet

₹22.0/Tablet

Letroz Tablet

Sun Pharmaceutical Industries Ltd

₹39.2/tablet

78% costlier

Stimufol 2.5mg Tablet

Intas Pharmaceuticals Ltd

₹33.19/tablet

51% costlier

Fempro Tablet

Cipla Ltd

₹7.21/tablet

67% cheaper

Mamazol Tablet

Khandelwal Laboratories Pvt Ltd

₹12/tablet

45% cheaper

Letero Tablet

Hetero Drugs Ltd

₹7.15/tablet

68% cheaper

View all substitutes

Quick tips

You have been prescribed Letrafem 2.5 Tablet for the treatment of breast cancer or infertility due to anovulation.
It can be taken with or without food.
Do not drive or do anything requiring concentration until you know how Letrafem 2.5 Tablet affects you.
It may cause increased sweating and hot flushes. Try to keep cool by wearing light and airy clothes.
Your doctor may monitor your cholesterol level and bone mineral density (BMD) regularly as Letrafem 2.5 Tablet can alter their levels.
Do not take Letrafem 2.5 Tablet if you are pregnant or breastfeeding

Fact Box

Chemical Class

Diphenylmethane Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Aromatase inhibitor

Patient concerns

Breast pain not able to sleep already take test no cancer but pain

Dr. Megha Gupta

Obstetrics and Gynaecology

Hi Rajeshwari. Breast pain can be due to hormonal changes as well. Please visit a gynaecologist in your area for a thorough evaluation.

If any symtom of brest cancer if have whats the cure

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

First is confirmation of breast cancerChance of cure depends on stage of cancer

FAQs

Why have I been prescribed Letrafem 2.5 Tablet?

Letrafem 2.5 Tablet is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy. It is also used to treat infertility caused due to anovulation (during menstrual cycle egg cell from ovaries is not released).

How does Letrafem 2.5 Tablet work?

Letrafem 2.5 Tablet is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for the production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent cancer from growing.

For how long should I take Letrafem 2.5 Tablet?

If the breast tumor is in the advanced stage or has spread to other parts of the body, it is recommended that you continue taking Letrafem 2.5 Tablet till the tumor shows progression. In cases where Letrafem 2.5 Tablet is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until the tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Letrafem 2.5 Tablet followed by 3 years of tamoxifen.

If I am taking irbesartan to control my blood pressure, can I take Letrafem 2.5 Tablet?

Yes, you can take irbesartan and Letrafem 2.5 Tablet together. However, be careful and keep a regular check on your blood pressure since Letrafem 2.5 Tablet may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.

Does Letrafem 2.5 Tablet affect vision?

Although it is very uncommon, Letrafem 2.5 Tablet may cause a cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.

My friend who is taking Letrafem 2.5 Tablet often sweats a lot. Is it because of Letrafem 2.5 Tablet?

This could be a sign of hot flushes which is a very common side effect of Letrafem 2.5 Tablet. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Letrafem 2.5 Tablet. However, in some people, the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.

What are the serious side effects of Letrafem 2.5 Tablet?

The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Letrafem 2.5 Tablet include stroke, angina, heart attack, blood clotting, cataract, osteoporosis, and severe skin reactions.

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Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Related ayurvedic ingredients

Olive oil

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1762.
Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 718.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 786-87.
Letrozole. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 1997 [revised Jan. 2014]. [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
National Health Service. Letrozole. [Last Reviewed: 21 Jul 2020]. [Accessed 08 Jul. 2023]. (online) Available from:
Letrozole [Package Insert]. Mumbai, India: HOPE Lifecare. [Accessed 08 Jul. 2023]. (online) Available from:
Letrozole [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2020. [Accessed 08 Jul. 2023]. (online) Available from:

Marketer details

Name: Adley Formulations

Address: Adley Formulation, SCO- 42, Sector 12, Panchkula-134112, Haryana, India

Country of origin: India

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