Esentra 120 Injection is a medicine used in the treatment of osteoporosis in postmenopausal women and in men at increased risk of fractures. It makes the bones strong and reduce the risk of fractures.

is used in the treatment osteoarthritis

Uses of Esentra Injection

Osteoporosis

Benefits of Esentra Injection

In Osteoporosis

Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause. This condition can be treated with bone-strengthening medicines. Esentra 120 Injection slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. The injection is given by a doctor or nurse and should not be self-administered.
You can help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.

Side effects of Esentra Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Esentra

Musculoskeletal (bone, muscle or joint) pain
Pain in extremities
Nerve pain
Constipation
Rash
Urinary tract infection

How to use Esentra Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Esentra 120 Injection. Please consult your doctor.

Pregnancy

UNSAFE

Esentra 120 Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

SAFE IF PRESCRIBED

Esentra 120 Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

SAFE

Esentra 120 Injection does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Esentra 120 Injection is safe to use in patients with kidney disease. No dose adjustment of Esentra 120 Injection is recommended.

Liver

SAFE IF PRESCRIBED

Esentra 120 Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Esentra 120 Injection may not be needed in these patients. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Esentra 120 Injection

₹24000.0/Injection

Denoci 120mg Injection

Cipla Ltd

₹31350/injection

31% costlier

Denosurel 120mg Injection

Reliance Life Sciences

₹28500/injection

19% costlier

Quick tips

Esentra 120 Injection is a medication used to treat thinning of the bones (called osteoporosis).
Take calcium and vitamin D to help build your bones when taking Esentra 120 Injection.
Do not take if you are pregnant or plan to become pregnant.
May cause a rare problem of the jaw (osteonecrosis), mostly seen after a dental procedure. Tell your doctor if you develop sudden jaw pain.
Esentra 120 Injection may also increase the risk of infection. Avoid being close to people with cold, flu or other contagious illnesses.
Tell your doctor if you develop a rash while taking Esentra 120 Injection.

Fact Box

Chemical Class

Monoclonal antibody (mAb)

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Bone resorption inhibitors- Monoclonal antibodies

Patient concerns

Teriparatide is this injection advisable?

Dr. Akshat Goel

Orthopaedics

Yes, it's good in Osteoporosis

Details About osteoporosis treatment

Dr. Akshat Goel

Orthopaedics

Take Calcium and Vitamin-D3 supplements

FAQs

How long can you stay on Esentra 120 Injection?

There is no optimal duration of treatment of osteoporosis with Esentra 120 Injection. The patient’s response and tolerability to the medicine is continuously monitored through periodic assessments, especially after 5 years of use of Esentra 120 Injection. Depending on this, the duration of taking Esentra 120 Injection is decided.

Does Esentra 120 Injection cause hair loss?

Yes, hair loss is a common side effect of Esentra 120 Injection though it does not affect everyone. Discuss with your doctor if you have concerns regarding your hair loss.

Is Esentra 120 Injection a chemotherapy drug?

Esentra 120 Injection is not a chemotherapy drug. It is a protein (monoclonal antibody) that interferes with the action of another protein in order to treat bone loss and osteoporosis. Treatment with Esentra 120 Injection makes the bones stronger and less likely to break.

How is Esentra 120 Injection given and how often?

Esentra 120 Injection is available as an injection and is given by a healthcare professional. It is given once in 6 months. Your doctor may also advise you to take calcium and vitamin D while taking Esentra 120 Injection.

Can Esentra 120 Injection be taken during pregnancy?

No, pregnant women should not take Esentra 120 Injection. You must use an effective method of birth control during and for at least 5 months after the last dose of Esentra 120 Injection if you can become pregnant.

How should Esentra 120 Injection be stored?

Esentra 120 Injection should be stored in a refrigerator at 36°F to 46°F (2°C to 8°C) in the original carton. Warm temperatures can make it ineffective, and therefore proper storage is necessary. When you remove it from the refrigerator, keep it at room temperature [up to 77°F (25°C)] in the original carton and use it within 14 days.

Does Esentra 120 Injection cause osteonecrosis of the jaw?

Osteonecrosis is a rare side effect of Esentra 120 Injection. It refers to the damage caused to the bone of jaw. To avoid this, you should maintain good oral hygiene and receive routine dental check ups while taking Esentra 120 Injection. Contact your doctor and dentist immediately if you experience any problems with your mouth or teeth such as loose teeth, discharge, pain or swelling, or non-healing of sores. These could be signs of osteonecrosis of jaw.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 766.
Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1299.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 370.
Drugs.com. Denosumab. [Accessed 02 Apr. 2019] (online) Available from:
Denosumab. Milton Road, Cambridge: Amgen Ltd.; 2010 [revised Jun. 2018]. [Accessed 02 Apr. 2019] (online) Available from:

Marketer details

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.