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PhD (Pharmacology), PGDPRA
Reviewed By
MD Pharmacology, MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Combunex 800 Tablet

Prescription Required
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Introduction of Combunex Tablet

Combunex 800 Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.

Combunex 800 Tablet is a combination of two antibiotics: isoniazid and ethambutol which treat tuberculosis.

Uses of Combunex Tablet

Benefits of Combunex Tablet

In Treatment of Tuberculosis (TB)

Tuberculosis is an infectious disease that mainly affects the lungs but can affect other parts of the body as well. Combunex 800 Tablet helps treat tuberculosis by stopping the growth of bacteria causing infection. Your symptoms might improve after using Combunex 800 Tablet. However, make sure to complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.

Side effects of Combunex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Combunex

  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Increased liver enzymes
  • Jaundice
  • Increased uric acid level in blood
  • Gout
  • Visual impairment

How to use Combunex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combunex 800 Tablet is to be taken empty stomach.
Avoid Combunex 800 Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking Combunex 800 Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Combunex 800 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Combunex 800 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Combunex 800 Tablet may cause side effects which could affect your ability to drive.
Combunex 800 Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Combunex 800 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Combunex 800 Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Combunex 800 Tablet should be used with caution in patients with liver disease. Dose adjustment of Combunex 800 Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Combunex 800 Tablet
₹9.57/Tablet
Myconex 800 Tablet
Cadila Pharmaceuticals Ltd
₹9.16/tablet
4% cheaper
Econex 300mg/800mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹7.67/tablet
20% cheaper
Iso Koxi 300 mg/800 mg Tablet
Shreya Life Sciences Pvt Ltd
₹9.67/tablet
1% costlier
₹6.73/tablet
30% cheaper
Visocox 300 mg/800 mg Tablet
Shrinivas Gujarat Laboratories Pvt Ltd
₹7.19/tablet
25% cheaper

Quick tips

Combunex Tablet

  • Combunex 800 Tablet should be taken on an empty stomach but at the same time every day.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Combunex 800 Tablet affects you.
  • It is advisable to stay hydrated and drink plenty of water to overcome medicine side effects.
  • Avoid consuming alcohol while taking this medication as it can enhance the dizziness.
  • Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.

Fact Box

Habit Forming
No
Therapeutic Class
ANTI INFECTIVES

Patient concerns

Patient concerns

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My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???
Dr. Rahul Yadav
Paediatrics
Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.
Though took vaccines in childhood, the test for TB came positive. Was advised to undergo treatment.physically absolute fit and healthy, is it advisable to take treatment?
Dr. Anshum Aneja Arora
Pulmonology
If sputum is positive for Tb , treatment is absolutely essential. Read more at www.arohealth.com/tuberculosis
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 09 Apr. 2019] (online) Available from:External Link
  2. Ethambutol. Ontario, Canada: Patheon Inc.; 2007. [Accessed 09 Apr. 2019] (online) Available from:External Link
  3. Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 09 Apr. 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 09 Apr. 2019] (online) Available from:External Link

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